End-Expiratory Lung Volume in Children Awakening From Propofol Anesthesia

Not Applicable

Recruiting

• Conditions: Atelectasis, Postoperative Pulmonary
• Interventions: Other: Head elevation_L; Other: Head elevation_H; Other: Supine_L; Other: Supine_H

• Registration Number: NCT05821114
• Lead Sponsor: Seoul National University Hospital

Brief Summary

The goal of this pilot randomized clinical trial is to test the effects of high flow nasal oxygen and head elevation during awakening from propofol anesthesia in pediatric patients undergoing airway surgery.

The main question\[s\] it aims to answer are:

* High flow oxygen can decrease the occurence of atelectasis during awakening from propofol anesthesia in pediatric patients?

* Head elevation can decrease the occurence of atelectasis during awakening from propofol anesthesia in pediatric patients?

Researchers will compare high flow oxygen vs low flow oxygen group to see if the use of high flow oxygen decrease the occurence of atelectasis during awakening from propofol anesthesia.

And in each group, the patients will be assigned to supine position vs head elevation position to compare the effects of head elevation during awakening from propofol anesthesia.

Detailed Description

Not available

Study Timeline

• Status Verified: 2023-04
• Study Start: 2023-04-07
• Study First Submitted: 2023-04-07
• Study First Submitted QC: 2023-04-07
• Last Update Submitted: 2023-04-07
• Study First Posted: 2023-04-20
• Last Update Posted: 2023-04-20
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

• Pediatric patients undergoing airway surgery with high flow nasal oxygen

Exclusion Criteria

• Loss of spontaneous ventilation during surgery
• less than 1 months
• cyanotic patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Low flow oxygen	Supine_L	Oxygen supply (0.3L/kg/min.) during awakening from propofol anesthesia
high flow oxygen	Supine_H	Oxygen supply (2L/kg/min.) during awakening from propofol anesthesia
Low flow oxygen	Head elevation_L	Oxygen supply (0.3L/kg/min.) during awakening from propofol anesthesia
high flow oxygen	Head elevation_H	Oxygen supply (2L/kg/min.) during awakening from propofol anesthesia

Primary Outcome Measures

Name	Time	Method
Changes in Electric Impedance Tomography parameter	from induction of anesthesia to end of operation, about 3 hours

Trial Locations

Locations (1)

Hee-Soo Kim; 🇰🇷 Seoul, Korea, Republic of