Effect of Sildenafil on the Development of Retinopathy of Prematurity in Preterm Infants
Phase 2
- Conditions
- Vision Disorder.Retinopathy of prematurity Retrolental fibroplasia
- Registration Number
- IRCT2015102314215N3
- Lead Sponsor
- Vice chancellor for research, Ahvaz Jundishapur University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
newborns with gestational age less than 32 weeks; need to oxygen therapy.
Exclusion criteria: blood sugar= 150mg% more than 7 days; metabolic acidosis (pH< 7.2) more than 24h; blood transfusion greater than 10ml/kg in first 4 weeks of life; sepsis with fungi.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Retinopathy stage 1. Timepoint: at 32 postconceptual age till 45 weeks postconceptual age. Method of measurement: Retinoscopy.
- Secondary Outcome Measures
Name Time Method Stage2-5 retinopathy. Timepoint: at 32 till 45 weeks postconceptual age. Method of measurement: Retinoscopy.;The period of NCPAP therapy. Timepoint: Hour. Method of measurement: Use of NCPAP.;Period of Mechanical Ventilation therapy. Timepoint: Hour. Method of measurement: Use of ventilator.;Period of oxygen therapy. Timepoint: Hour. Method of measurement: Use of oxygen.