Feasibility study of interval compressed regimen using four-drugs for osteosarcoma

Not Applicable

• Conditions: Neoplasms

• Registration Number: KCT0004198
• Lead Sponsor: ational Cancer Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 August 2019
• Study Completion: 2022-12-31

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 53

Inclusion Criteria

newly diagnosed osteosarcoma patients aged 5 to 50 years
*control group: aged 19 to 40 years, who denied acute or chronic disease, 15 patients with each gender

Exclusion Criteria

patients with impaired organ function
patients who cannot meet the criteria below
-renal function: CCr or GFR or eGFR = 70 mL/min/1.73 m2, liver function: AST/ALT = 5 x upper limit, total bilirubin = 1.5 x upper limit of normal for age, heart function : shortening fraction = 24% or ejection fraction = 50% (Echo), lung function: no respiratory compromise, SaO2 =95% at room air, bone marrow: ANC = 750/uL and platelet = 75,000/uL
patients who do not agree this protocol
pregnant or lactating woman
hypersensitivity to drugs in this study
patients who received prior chemotherapy

Study & Design

• Study Type: Interventional Study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
tumor necrosis rate

Secondary Outcome Measures

Name	Time	Method
safety profile according to CTCAR ver.4.0