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临床试验/NCT05639582
NCT05639582已完成不适用

Evaluation of Trabecular Bone Changes in Individuals With Periodontal Disease Using Fractal Analysis

Necmettin Erbakan University1 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2020年11月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
200
试验地点
1
主要终点
Evaluation of the effect of periodontal disease on alveolar bone by fractal analysis

研究概览

简要总结

In this study, the effects of periodontal disease on alveolar bone were investigated using fractal analysis method.

详细描述

Background: It is very difficult to objectively evaluate the negative changes in bone structure due to periodontitis. The present study was aimed to evaluate the trabecular bone changes between healthy individuals and periodontitis patients by fractal dimension analysis on digital panoramic radiographs.

Method: The study included 50 periodontally healthy individuals (control group), 50 individuals with Stage 1 periodontitis (S1-P group), 50 individuals with Stage 2 periodontitis (S2-P), and 50 individuals with Stage 3 periodontitis (S3-P), a total of 200 individuals were included. The fractal dimension (FD) value of the trabecular bone in the interproximal space between mandibular first molar and second premolar tooth roots was evaluated using Image J program. The mean fractal dimension values of the two regions were calculated by box counting method.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • 18-65 years old
  • Getting a diagnosis of stage 1,2 and 3 periodontitis
  • Be diagnosed as periodontally healthy
  • Have no barriers to obtaining radiographs
  • Not having any systemic disease that may affect periodontal status
  • Not smoking and alcohol use
  • Volunteer to participate in the study

排除标准

  • Those who use drugs that can affect bone metabolism
  • Radiographs with poor diagnostic quality
  • Root canal treatment or teeth with periapical lesions in the area of interest
  • Individuals who have suffered a fracture or trauma that affects the anatomy or integrity

结局指标

主要结局

Evaluation of the effect of periodontal disease on alveolar bone by fractal analysis

时间窗: baseline

Fractal dimension evaluation can give an objective result about the effect of periodontal disease on alveoler bone, since it shows changes in bone trabeculation numerically.

次要结局

  • gingival index(baseline)
  • Probing pocket depth(baseline)
  • plaque index(baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Ummuhan Tekin Atay

Principal Investigator

Necmettin Erbakan University

研究点 (1)

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