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A clinical trial to evaluate the quality of life with AYUSH QOL 2C in patients of Non metastatic breast cancer as an adjuvant to chemotherapy

Phase 2
Conditions
Health Condition 1: null- Female Non Metastatic Breast Cancer patients receiving Chemotherapy
Registration Number
CTRI/2010/091/001247
Lead Sponsor
CCRAS AYUSH New Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
80
Inclusion Criteria

Patients of breast cancer.

Age eligibility for study : 18 years and older

Gender eligible for study : Female

Disease characteristics : Histologically confirmed Cancer breast

Patient characteristics : Over 18 years, of age

Performance status : ECOG grade up to 2

Life expectancy : At least 3 months

Haematopoietic : WBC greater than 4000/mm3

Platelet count > 100,000 mm3

Hepatic : Bilirubin less than 1.5 mg/ dl

SGOT & SGPT more than 2 times normal

Renal : Creatinine less than 1.5 mg/ dl

Other : No concurrent active infection.

No prior malignancy.

Not pregnant or nursing

Effective contraception for all Prior : Biologic therapy: not specified

Chemotherapy : no prior chemotherapy

Exclusion Criteria

Known secondary neoplasia or central nervous system metastases. Acute or chronic leukemias. Lymphoma or multiple myeloma.
Body weight below 40 kg
Female patients who are pregnant or breast feeding or adults of reproductive potential not employing effective birth control measures Concurrent severe or uncontrolled medical disease.
Acute or chronic liver disease.
Confirmed diagnosis of HIV.
Uncontrolled diabetes.
Surgery less than 2 weeks prior to entry ( or not recovered from effects of surgery)

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
TO EVLUATE THE EFFICACY OF AYUSH QOL 2C in improving Quality of Life [QOL]in non metastatic breast cancer female patients receiving chemotherapyTimepoint: Every 21 days till patient receives 4 or 8 chemotherapy cycles & at 6th month, 9th month, & final follow up at one year.
Secondary Outcome Measures
NameTimeMethod
TO MONITOR THE SAFETY OF AYUSH QOL 2C in FEMALE PATIENTS WITH non-metastatic BREAST CANCER AS AN ADJUVANT to CHEMOTHERAPYâ?? <br/ ><br> <br/ ><br>â??TO ASSESS THE IMPROVEMENT IN QUALITY OF LIFE OF BREAST CANCER PATIENTS SUFFERING FROM GRADE I ,II & III receiving CHEMOTHERAPY FOLLOWING ADMINISTRATION of AYUSH QOL 2C as supplement to chemotherapy at each chemotherapy cycle and at 6 months and one year AFTER THE TREATMENTâ?? <br/ ><br>Timepoint: Every 21 days till patient receives 4 or 8 chemotherapy cycles & at 6th month, 9th month, & final follow up at one year.
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