Impact of Helicobacter Pylori Infection on Prolactin Levels in Reproductive-Age Women in Upper Egypt
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 75
- 主要终点
- Prolactin Levels:
研究概览
简要总结
The research is a cross-sectional observational study conducted at Assiut University Hospital. It will involve 75 women aged 18-45 with confirmed H. pylori infection. The study will measure serum prolactin levels and H. pylori infection status through stool antigen tests. The primary outcome is comparing prolactin levels between H. pylori-positive and negative women. Secondary outcomes include analyzing correlations with clinical symptoms and demographic factors.
详细描述
Study Design and Setting Cross-sectional observational study
Conducted at Assiut University Hospital
Sample size: 75 women
Participants Inclusion criteria: Women aged 18-45, confirmed H. pylori infection, reproductive age
Exclusion criteria: Recent antibiotic or PPI use, endocrine disorders, chronic illnesses affecting prolactin
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 48 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age Range: Women aged 18 to 45 years.
- •Diagnosis of H. pylori Infection: Participants must have a confirmed diagnosis of H. pylori infection through non-invasive methods such as stool antigen tests or breath tests and IgM serum.
- •Reproductive Age: Women must be within reproductive age and not currently pregnant or breastfeeding
排除标准
- •Recent Antibiotic Use: Individuals who have taken antibiotics within the last month will be excluded to avoid interference with H. pylori detection.
- •Use of Proton Pump Inhibitors (PPIs): Patients using PPIs or other medications that affect gastric acid secretion within the last month will be excluded.
- •Endocrine Disorders: Women with known endocrine disorders such as hyperprolactinemia from other causes will be excluded.
- •Chronic Illnesses: Individuals with chronic illnesses that could affect prolactin levels (e.g., renal failure, liver disease) will also be excluded.
结局指标
主要结局
Prolactin Levels:
时间窗: 1 month
Prolactin Levels: The primary outcome measure will be the serum prolactin levels in women diagnosed with H. pylori infection compared to those without infection.
次要结局
未报告次要终点
研究者
Sandra Maged Ezzat Rasmi
resident at the internal medicine department
Assiut University