A Retrospective Study on Efficacy and Safety of Guduchi Ghan Vati for Covid-19 Asymptomatic Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 91
- 试验地点
- 1
- 主要终点
- Virologic clearance
研究概览
简要总结
Coronavirus disease 2019 (Covid-19) has been declared global emergency with immediate safety, preventative and curative measures to control the spread of virus. Confirmed cases are treated with clinical management as they are diagnosed but so far, there is no effective treatment or vaccine yet for Covid-19.
With recommended guidelines of AYUSH Ministry, India, the use of Ayurveda for Covid-19 has increased; however, its efficacy and safety in Covid-19 confirmed patients remain unclear.
Present study examined the efficacy and safety of one of the recommended Ayurveda drug (Guduchi Ghan Vati) compared with standard care for patients with asymptomatic Covid-19 patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 18
- •A person diagnosed with COVID-19
- •Asymptomatic at the time of admission
排除标准
- •Patients over 75 years
- •Taking antibiotics or antiretroviral for any reason
- •Mild to Moderate symptoms at the time of hospital admission
研究组 & 干预措施
Ayurveda
Guduchi Ghan Vati was given to Covid patients 2 tablets (500 mg each) twice daily were given orally after meal for 28 days. Guduchi ghan vati is a powdered aqueous extract of Tinospora cordifolia in tablet form and prepared in GMP certified Pharmacy of the University, following standard protocol.
干预措施: Guduchi Ghan Vati (Drug)
结局指标
主要结局
Virologic clearance
时间窗: 21 days
Virologic clearance indicates the duration from the first Covid-19 positive result to the first Covid-19 negative result
次要结局
- Change in the number of patients going from asymptomatic to moderately disease(10-days of hospital admission)
- Hospital Stay(21 days)
- Clinically relevant adverse effects(21-days)