Effectiveness of Mulligan Joint Mobilizations and Trunk Stabilization Exercises Versus Isometric Knee Strengthening in the Management of Knee Osteoarthritis: a Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Change from baseline Knee injury and Osteoarthritis Outcome Score (KOOS) at 6 weeks
研究概览
简要总结
Knee joint arthritis posses a serious health problem and caring for an individual with knee osteoarthritis (KOA) produces a great burden on society. Knee joint pain is associated with physical activity while performing various activities of daily living (ADL) in patients with early and severe osteoarthritis (OA). In addition to knee pain, physical function or daily activity is strongly influenced by the severity of Osteoarthritis of the knee. Mulligan joint mobilization with movement provides evident effects on decreasing the pain and restoring the joint biomechanics. Trunk stabilization exercise will improve the stability of trunk which distributes the weight of body evenly on both feets. The aim of this study is to determine the effects of mulligan joint mobilization and trunk stabilization exercise on pain, disability and submaximal exercise performance in KOA.
详细描述
A randomized control trial will be conducted at IPM&R on 60 subjects with knee osteoarthritis and age between 40-60 years. Initial screening of the subjects will be carried out by the referring consultant. Subjects who fulfilled the study criteria will be recruited using computer generated random sampling after explaining the study objective and taken written informed consent. All participants will be evaluated using visual analogue scale, Knee injury and Osteoarthritis Outcome Score and 6-minute walk test for pain severity, functional limitation and submaximal exercise capacity at 1st, 3rd and 6th week. The subjects will be allocated into three groups through computer generated random allocation. Group 1 will receive mulligan mobilization with kinesiotaping and knee strengthening. Group 2 will receive trunk stabilization exercise, knee strengthening and Kinesiotaping. Group 3 will receive knee strengthening along with kinesiotaping. A drop-out rate of 9 will be taken. Recorded data will be entered and analysed using SPSS version 21. Mean and SD will be calculated of quantitative variables like age, pain, knee related function, submaximal exercise capacity and stair climb by using repeated measure ANOVA. For pair wise comparison, post hoc tukey will be applied. Value of equal to or less than 0.05 will be considered significant.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
盲法说明
After confirming eligibility, the physiotherapist performing intervention obtained treatment assignment (S.S. Ali). The subject will not be aware of the group allocation and different time slot will be given for the intervention. Another physiotherapist who will not be aware of allocation concealment, record the reading of outcomes at the baseline, after three and six weeks
入排标准
- 年龄范围
- 40 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Both gender (female and male) patients
- •Age between 40 - 60
- •Knee osteoarthritis Grade I & II on Kellgren and Lawrence (K/L) criteria
- •Prediagnosed case of knee OA as per the American College of Rheumatology (ACR).
排除标准
- •Known skin allergies
- •Sensory-motor dysfunction of lower extremity
- •Severe joint deformity of lower extremity
- •Post Traumatic Arthritis
- •Constitutional Symptoms (Fever, Malaise, Weight Loss and high blood pressure)
- •Knee Intraarticular injection in past 3 months
- •Acute low back pain
- •History of spinal surgery
- •Subject using assistive devices for ambulation i.e. cane, walkers, sticks
- •Refused to give consent
- •Body Mass Index > 30 kg/m2
- •Received physiotherapy treatment in the past 3 months
- •Visual Analogue Scale <4
- •Patellofemoral joint arthritis will be excluded
结局指标
主要结局
Change from baseline Knee injury and Osteoarthritis Outcome Score (KOOS) at 6 weeks
时间窗: baseline and post intervention (week 6 - the analysis will be conducted on the first week immediately after the end of the training
The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self reported specific joint measure developed to assess a broad spectrum of patients with knee injuries and OA, for pain and other symptoms, function in daily life, function in sports and recreation, and quality of knee-related life, being easy to use, evaluating the short- and long-term health problems related to the knee joint. The KOOS contains 42 items covering five subscales: pain, other symptoms, activities of daily living, sport and leisure activities and quality of life. A score of 0 (extreme problems) 100 (smoothly) can be obtained separately for each sub-range.
次要结局
- Knee injury and Osteoarthritis Outcome Score (KOOS)(baseline, 3 weeks and 6 weeks)
- Stairs Climb Test(baseline, 3 weeks and 6 weeks)
- 6 Minute Walk Test(baseline, 3 weeks and 6 weeks)
- Visual Analogue Scale(baseline, 3 weeks and 6 weeks)
研究者
Shaikh Nabi Bukhsh Nazir
Principal Investigator
Dow University of Health Sciences