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Investigation on the Duration of Extended Adjuvant Letrozole treatment.

Recruiting
Conditions
breast cancer, post-menopausal, aromatase inhibitor, letrozole, extended hormonal therapymamma carcinoom, aromatase remmer, verlengde hormonale therapie
Registration Number
NL-OMON23112
Lead Sponsor
eiden University Medical Center (LUMC)
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
1823
Inclusion Criteria

1. Postmenopausal at the time of randomization;

2. Histologically proven invasive breast cancer (stage I, II, or III) adequately treated at the time of diagnosis;

Exclusion Criteria

1. ER and PgR negative or unknown primary tumors;

2. Evidence of previous or current localized or distant breast cancer recurrence;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Disease free survival (DFS).
Secondary Outcome Measures
NameTimeMethod
1. Overall survival;<br /><br>2. Distant disease free survival;<br /><br>3. Contralateral breast cancer;<br /><br>4. Safety.
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