Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Phase 3

Completed

Conditions: Recurrent Breast Carcinoma
Stage IA Breast Cancer
Stage IB Breast Cancer
Stage IIIA Breast Cancer
Estrogen Receptor Positive Breast Cancer
Progesterone Receptor Positive Tumor
Stage IIA Breast Cancer
Stage IIB Breast Cancer

Interventions: Other: Laboratory Biomarker Analysis
Drug: Exemestane
Other: Quality-of-Life Assessment
Procedure: Oophorectomy
Drug: Tamoxifen
Radiation: Radiation Therapy
Drug: Triptorelin

Registration Number: NCT00066690

Lead Sponsor: ETOP IBCSG Partners Foundation

Brief Summary: RATIONALE: Estrogen can stimulate the growth of breast tumor cells. Ovarian function suppression combined with hormone therapy using tamoxifen or exemestane may fight breast cancer by reducing the production of estrogen. It is not yet known whether suppression of ovarian function plus either tamoxifen or exemestane is more effective than tamoxifen alone in preventing the recurrence of hormone-responsive breast cancer.

PURPOSE: This randomized phase III trial studies ovarian suppression with either tamoxifen or exemestane to see how well they work compared to tamoxifen alone in treating premenopausal women who have undergone surgery for hormone-responsive breast cancer.

Detailed Description: OBJECTIVES:

* Compare the disease-free survival, breast cancer-free interval, distant recurrence-free interval and overall survival of premenopausal women with endocrine-responsive breast cancer when treated with tamoxifen + ovarian function suppression (by triptorelin, oophorectomy, or ovarian irradiation) or exemestane + ovarian function suppression vs. tamoxifen alone. The primary comparison is ovarian function suppression with either tamoxifen or exemestane vs. tamoxifen alone.

* Compare the quality of life, including late side effects of early menopause, of patients treated with these regimens.

OUTLINE: This is a randomized, multicenter study. Patients are stratified according to participating center, prior adjuvant/neoadjuvant chemotherapy (yes vs no), and number of positive axillary and/or internal mammary lymph nodes (0 vs 1 or more) and intended initial method of ovarian function suppression (triptorelin vs oophorectomy vs ovarian irradiation). Treatment duration is 5 years. Patients are followed every 3 months for 1 year, every 6 months for 5 years, and then annually thereafter. Quality of life is assessed at baseline, every 6 months for 2 years, and then annually for 4 years.

Recruitment & Eligibility

Status: COMPLETED

Sex: Female

Target Recruitment: 3066

Inclusion Criteria

Premenopausal women (estradiol [E2] in the premenopausal range [according to institution parameters]) who meet the following criteria:
- Patients who did not receive chemotherapy should be randomized within 12 weeks after definitive surgery; such patients should have estradiol (E2) in the premenopausal range following surgery; the only patients who do not require testing of estradiol (E2) to confirm premenopausal status are those who have been menstruating regularly during the 6 months prior to randomization and have not used any form of hormonal contraception or any other hormonal treatments during the 6 months prior to randomization
- Patients who received prior adjuvant and/or neoadjuvant chemotherapy should be randomized after completing chemotherapy and within 8 months of the final dose of chemotherapy as soon as premenopausal status is confirmed; all such patients should have premenopausal status confirmed by an estradiol (E2) in the premenopausal range between 2 weeks and 8 months after completing chemotherapy
- Adjuvant trastuzumab (Herceptin ®) is allowable, and is not considered to be chemotherapy for eligibility timing determination
- Patients with temporary chemotherapy-induced amenorrhea who regain premenopausal status within eight months of the final dose of chemotherapy are eligible; (please note that some patients taking tamoxifen or aromatase inhibitors, even without evidence of menses, may have ovarian function recovery following chemotherapy and resume estradiol secretion); in patients wishing to participate in the study, with postmenopausal hormone levels shortly after chemotherapy, it is recommended to recheck their estradiol level at a later timepoint within 8 months of completing chemotherapy, even in the absence of return of menses
Histologically proven, resected breast cancer; pathology material should be available for submission for central review as part of the quality control measures for this protocol
Patients must have hormone receptor positive tumors; if there is more than one breast tumor, each tumor must be hormone receptor positive; hormone receptors must be determined using immunohistochemistry; estrogen receptor (ER) and/or progesterone receptor (PgR) must be greater than or equal to 10% of the tumor cells positive by immunohistochemical evaluation; biochemical determination alone is not acceptable
The tumor must be confined to the breast and axillary nodes without detected metastases elsewhere, with the exception of tumor detected in internal mammary chain nodes by sentinel node procedure; patients who received neoadjuvant therapy must have had operable disease prior to neoadjuvant treatment to be eligible; patients who had a pathological evaluation with tru cut or core biopsy of invasive breast cancer prior to neoadjuvant therapy and were found to have no invasive tumor in the pathological specimen from definitive surgery are eligible; for these patients, pre-neoadjuvant tumor characteristics will be used for defining eligibility; in case of persistent disease, pathology findings from the definitive surgery should be used
Patients must have had proper surgery for primary breast cancer with no known clinical residual loco-regional disease:
- A total mastectomy; radiotherapy is optional after mastectomy OR
- A breast-conserving procedure (lumpectomy, quadrantectomy or partial mastectomy with margins clear of invasive cancer and ductal breast carcinoma in situ [DCIS]); the local pathologist must document negative margins of resection in the pathology report; if all other margins are clear, a positive posterior (deep) margin is permitted, provided the surgeon documents that the excision was performed down to the pectoral fascia and all tumor has been removed; likewise, if all other margins are clear, a positive anterior (superficial; abutting skin) margin is permitted provided the surgeon documents that all tumor has been removed; radiation therapy to the conserved breast is required; patients may be randomized before, during or after completion of radiation therapy to the breast
Either axillary lymph node dissection (pathological examination of at least 6 nodes recommended) or a negative axillary sentinel node biopsy (pN0[sn]) is required; patients with negative or microscopically axillary positive sentinel nodes (pN1mi: micrometastasis none > 2.0 mm) do not require further axillary therapy; those with positive sentinel nodes must have either an axillary dissection or radiation of axillary nodes
For International Breast Cancer Study Groups (IBCSG) centers, patients must have completed baseline Quality of Life (QL) Forms prior to randomization; the only exceptions are cognitive or physical impairment that interferes with QL assessment or inability to read any of the languages available on IBCSG QL forms; for non-IBCSG centers, extent of participation in the QL study is to be determined at the activation of the trial for each cooperative group
Written informed consent must be signed and dated by the patient and the investigator prior to randomization
Patients must be accessible for follow-up
Patients must be informed of and agree to data and tissue material transfer and handling, in accordance with national data protection guidelines

Exclusion Criteria

Patients who are postmenopausal (i.e., do not have an estradiol [E2] level in the premenopausal range) after surgery or after chemotherapy, whichever is later
Patients with distant metastatic disease
Patients with locally advanced inoperable breast cancer including inflammatory breast cancer or supraclavicular node involvement or with enlarged internal mammary nodes (unless pathologically negative) are not eligible; patients with involved internal mammary nodes detected by sentinel node biopsy that are not enlarged are eligible
Patients with positive final margins (referring to only DCIS and invasive cancer, not lobular breast carcinoma in situ [LCIS]), except as noted; DCIS at a margin is permitted if a complete mastectomy has been performed
Patients with clinically detectable residual axillary disease
Patients with a history of prior ipsilateral or contralateral invasive breast cancer; patients with synchronous bilateral invasive breast cancer (diagnosed histologically within 2 months) are eligible if the bilateral disease meets all other eligibility criteria
Patients with previous or concomitant invasive malignancy are not eligible; the exceptions are patients with the following (and only the following) malignancies (previous or concomitant) who are eligible if adequately treated:
- Basal or squamous cell carcinoma of the skin
- In situ non-breast carcinoma without invasion
- Contra- or ipsilateral in situ breast carcinoma
- Non-breast invasive malignancy diagnosed at least 5 years ago and without recurrence:
  - Stage I papillary thyroid cancer
  - Stage Ia carcinoma of the cervix
  - Stage Ia or b endometrioid endometrial cancer
  - Borderline or stage I ovarian cancer
Patients with other non-malignant systemic diseases (cardiovascular, renal, hepatic, lung, etc.) that would prevent prolonged follow-up; patients with previous thrombosis (e.g., deep vein thrombosis [DVT]) and/or embolism can be included only if medically suitable
Patients who have had a bilateral oophorectomy or ovarian irradiation; patients who will be recommended to undergo oophorectomy within 5 years (e.g., breast cancer susceptibility gene [BRCA]1/2 gene carriers) and therefore for whom randomization to a treatment arm without OFS is inappropriate
Patients with a history of noncompliance to medical regimens and patients who are considered potentially unreliable
Patients who are pregnant or lactating at the time of randomization or who desire a pregnancy within 5 years; patients planning to use additional hormonal therapy apart from the randomized treatment during the next five years including all types of hormonal contraception; a pregnancy test is recommended for women of child-bearing potential who are sexually active and not using reliable contraceptive methods
Patients who received endocrine therapy (including neoadjuvant and adjuvant) for more than 8 months after their breast cancer diagnosis; patients who are receiving endocrine therapy at randomization (and have received it for less than 8 months) may continue such therapy until protocol-specified tamoxifen/exemestane is initiated
Patients who were taking tamoxifen or other selective estrogen receptor modulator (SERM) (e.g. Raloxifene) or hormone replacement therapy (HRT) within one year prior to their breast cancer diagnosis; prior oral contraceptives are allowed
Patients who have received GnRH analogues as part of their breast cancer treatment prior to randomization
Patients with psychiatric, addictive, or any disorder that would prevent compliance with protocol requirements

Study & Design

Study Type: INTERVENTIONAL

Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
T+OFS	Quality-of-Life Assessment	Tamoxifen 20mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
Tamoxifen	Laboratory Biomarker Analysis	Tamoxifen 20mg orally daily for 5 years
Tamoxifen	Quality-of-Life Assessment	Tamoxifen 20mg orally daily for 5 years
E+OFS	Laboratory Biomarker Analysis	Exemestane 25mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
E+OFS	Oophorectomy	Exemestane 25mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
E+OFS	Quality-of-Life Assessment	Exemestane 25mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
T+OFS	Radiation Therapy	Tamoxifen 20mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
T+OFS	Oophorectomy	Tamoxifen 20mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
T+OFS	Laboratory Biomarker Analysis	Tamoxifen 20mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
E+OFS	Radiation Therapy	Exemestane 25mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
Tamoxifen	Tamoxifen	Tamoxifen 20mg orally daily for 5 years
T+OFS	Triptorelin	Tamoxifen 20mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
T+OFS	Tamoxifen	Tamoxifen 20mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
E+OFS	Exemestane	Exemestane 25mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)
E+OFS	Triptorelin	Exemestane 25mg orally daily for 5 years plus ovarian function suppression (OFS; triptorelin (GnRH analogue) 3.75 mg by im injection q28 days for 5 years; or surgical oophorectomy; or ovarian irradiation)

Primary Outcome Measures

Name	Time	Method
Disease-free Survival	5-year estimates, reported at a median follow-up of 67 months.	Estimated percentage of patients alive and disease-free at 5 years from randomization, where disease-free survival is defined as the time from randomization to the first appearance of one of the following: invasive breast cancer recurrence at local, regional, or distant site, invasive contralateral breast cancer, second (non-breast) invasive cancer, or death without cancer event; or censored at date of last follow-up.

Secondary Outcome Measures

Name	Time	Method
Breast Cancer-free Interval	5-year estimates, reported at a median follow-up of 67 months.	Estimated percentage of patients alive and disease-free at 5 years from randomization, where breast cancer-free interval is defined as the time from randomization to invasive breast cancer recurrence at local, regional, or distant site, or invasive contralateral breast cancer; or censored at date of last follow up.
Distant Recurrence-free Interval	5-year estimates, reported at a median follow-up of 67 months.	Estimated percentage of patients alive and disease-free at 5 years from randomization, where distant recurrence-free Interval is defined as the time from randomization to invasive breast cancer recurrence at distant site, or invasive contralateral breast cancer; or censored at date of last follow up.
Overall Survival	8-year estimates, reported at a median follow-up of 8 years	Estimated percentage of patients alive at 8 years from randomization, where overall survival is defined as the time from randomization to death from any cause; or censored at date last known alive.

Trial Locations

Locations (495): Charlotte Hungerford Hospital Center for Cancer Care
🇺🇸
Torrington, Connecticut, United States
University of Chicago Comprehensive Cancer Center
🇺🇸
Chicago, Illinois, United States
Finley Hospital
🇺🇸
Dubuque, Iowa, United States
John Muir Medical Center-Concord Campus
🇺🇸
Concord, California, United States
Saint Mary Corwin Medical Center
🇺🇸
Pueblo, Colorado, United States
Johns Hopkins University/Sidney Kimmel Cancer Center
🇺🇸
Baltimore, Maryland, United States
Eisenhower Medical Center
🇺🇸
Rancho Mirage, California, United States
Odette Cancer Centre- Sunnybrook Health Sciences Centre
🇨🇦
Toronto, Ontario, Canada
Atlanta Regional CCOP
🇺🇸
Atlanta, Georgia, United States
Tufts Medical Center
🇺🇸
Boston, Massachusetts, United States
Massachusetts General Hospital Cancer Center
🇺🇸
Boston, Massachusetts, United States
Brigham and Women's Hospital
🇺🇸
Boston, Massachusetts, United States
Dana-Farber Cancer Institute
🇺🇸
Boston, Massachusetts, United States
Brigham and Women's Faulkner Hospital
🇺🇸
Boston, Massachusetts, United States
Beth Israel Deaconess Medical Center
🇺🇸
Boston, Massachusetts, United States
Cleveland Clinic Cancer Center/Fairview Hospital
🇺🇸
Cleveland, Ohio, United States
Cleveland Clinic Foundation
🇺🇸
Cleveland, Ohio, United States
Flower Hospital
🇺🇸
Sylvania, Ohio, United States
Upper Valley Medical Center
🇺🇸
Troy, Ohio, United States
University of Washington Medical Center
🇺🇸
Seattle, Washington, United States
Sidney and Lois Eskenazi Hospital
🇺🇸
Indianapolis, Indiana, United States
Saint Vincent Hospital and Health Care Center
🇺🇸
Indianapolis, Indiana, United States
University of Cincinnati
🇺🇸
Cincinnati, Ohio, United States
University of California San Diego
🇺🇸
San Diego, California, United States
Abbott-Northwestern Hospital
🇺🇸
Minneapolis, Minnesota, United States
San Francisco General Hospital
🇺🇸
San Francisco, California, United States
Kaiser Permanente San Leandro
🇺🇸
San Leandro, California, United States
Cancer Center of Kansas - El Dorado
🇺🇸
El Dorado, Kansas, United States
Cancer Center of Kansas-Kingman
🇺🇸
Kingman, Kansas, United States
Altru Cancer Center
🇺🇸
Grand Forks, North Dakota, United States
Via Christi Regional Medical Center
🇺🇸
Wichita, Kansas, United States
Cancer Center of Kansas - Parsons
🇺🇸
Parsons, Kansas, United States
Cancer Center of Kansas - Wellington
🇺🇸
Wellington, Kansas, United States
Cancer Center of Kansas-Independence
🇺🇸
Independence, Kansas, United States
Cancer Center of Kansas-Wichita Medical Arts Tower
🇺🇸
Wichita, Kansas, United States
Cancer Center of Kansas - Main Office
🇺🇸
Wichita, Kansas, United States
Lawrence Memorial Hospital
🇺🇸
Lawrence, Kansas, United States
Cancer Center of Kansas - Newton
🇺🇸
Newton, Kansas, United States
Memorial Hospital of Arkansas City
🇺🇸
Arkansas City, Kansas, United States
Abington Memorial Hospital
🇺🇸
Abington, Pennsylvania, United States
Saint Barnabas Medical Center
🇺🇸
Livingston, New Jersey, United States
Saint John Hospital and Medical Center
🇺🇸
Detroit, Michigan, United States
University of Oklahoma Health Sciences Center
🇺🇸
Oklahoma City, Oklahoma, United States
University of Hawaii Cancer Center
🇺🇸
Honolulu, Hawaii, United States
Mercy Medical Center - Des Moines
🇺🇸
Des Moines, Iowa, United States
Iowa Lutheran Hospital
🇺🇸
Des Moines, Iowa, United States
University of Alabama at Birmingham Cancer Center
🇺🇸
Birmingham, Alabama, United States
Denver Health Medical Center
🇺🇸
Denver, Colorado, United States
Presbyterian - Saint Lukes Medical Center - Health One
🇺🇸
Denver, Colorado, United States
Providence Saint Vincent Medical Center
🇺🇸
Portland, Oregon, United States
Kaiser Permanente
🇺🇸
Portland, Oregon, United States
East Bay Radiation Oncology Center
🇺🇸
Castro Valley, California, United States
Alta Bates Summit Medical Center-Herrick Campus
🇺🇸
Berkeley, California, United States
Mills - Peninsula Hospitals
🇺🇸
Burlingame, California, United States
Bay Area Tumor Institute
🇺🇸
Oakland, California, United States
Kaiser Permanente-Fremont
🇺🇸
Fremont, California, United States
Sutter Cancer Research Consortium
🇺🇸
Novato, California, United States
Scripps Cancer Center
🇺🇸
La Jolla, California, United States
USC / Norris Comprehensive Cancer Center
🇺🇸
Los Angeles, California, United States
Glendale Memorial Hospital and Health Center
🇺🇸
Glendale, California, United States
Bay Area Breast Surgeons Inc
🇺🇸
Emeryville, California, United States
Kaiser Permanente-Oakland
🇺🇸
Oakland, California, United States
UCLA / Jonsson Comprehensive Cancer Center
🇺🇸
Los Angeles, California, United States
Salinas Valley Memorial
🇺🇸
Salinas, California, United States
California Pacific Medical Center-Pacific Campus
🇺🇸
San Francisco, California, United States
Kaiser Permanente-San Francisco
🇺🇸
San Francisco, California, United States
UCSF Medical Center-Mount Zion
🇺🇸
San Francisco, California, United States
Porter Adventist Hospital
🇺🇸
Denver, Colorado, United States
Kaiser Permanente-San Diego Mission
🇺🇸
San Diego, California, United States
Veterans Administration-San Diego Medical Center
🇺🇸
San Diego, California, United States
Santa Rosa Memorial Hospital
🇺🇸
Santa Rosa, California, United States
Memorial Hospital Colorado Springs
🇺🇸
Colorado Springs, Colorado, United States
Kaiser Permanente Medical Center - Santa Clara
🇺🇸
Santa Clara, California, United States
SCL Health Saint Joseph Hospital
🇺🇸
Denver, Colorado, United States
Kaiser Permanente-South San Francisco
🇺🇸
South San Francisco, California, United States
Kaiser Permanente-Santa Teresa-San Jose
🇺🇸
San Jose, California, United States
John Muir Medical Center-Walnut Creek
🇺🇸
Walnut Creek, California, United States
Kaiser Permanente-Vallejo
🇺🇸
Vallejo, California, United States
North Colorado Medical Center
🇺🇸
Greeley, Colorado, United States
Denver Veterans Administration Medical Center
🇺🇸
Denver, Colorado, United States
Poudre Valley Hospital
🇺🇸
Fort Collins, Colorado, United States
The Shaw Regional Cancer Center
🇺🇸
Edwards, Colorado, United States
Front Range Cancer Specialists
🇺🇸
Fort Collins, Colorado, United States
SCL Health Lutheran Medical Center
🇺🇸
Wheat Ridge, Colorado, United States
North Suburban Medical Center
🇺🇸
Thornton, Colorado, United States
Hartford Hospital
🇺🇸
Hartford, Connecticut, United States
Jupiter Medical Center
🇺🇸
Jupiter, Florida, United States
MedStar Georgetown University Hospital
🇺🇸
Washington, District of Columbia, United States
Cancer Research Network Inc
🇺🇸
Boca Raton, Florida, United States
MedStar Washington Hospital Center
🇺🇸
Washington, District of Columbia, United States
Holy Cross Hospital
🇺🇸
Fort Lauderdale, Florida, United States
Augusta Oncology Associates PC-Saint Sebastian
🇺🇸
Augusta, Georgia, United States
Sibley Memorial Hospital
🇺🇸
Washington, District of Columbia, United States
Piedmont Hospital
🇺🇸
Atlanta, Georgia, United States
Northside Hospital
🇺🇸
Atlanta, Georgia, United States
Saint Joseph's Hospital of Atlanta
🇺🇸
Atlanta, Georgia, United States
Gwinnett Medical Center
🇺🇸
Lawrenceville, Georgia, United States
Dekalb Medical Center
🇺🇸
Decatur, Georgia, United States
Saint Joseph Medical Center
🇺🇸
Tacoma, Washington, United States
John H Stroger Jr Hospital of Cook County
🇺🇸
Chicago, Illinois, United States
Eureka Hospital
🇺🇸
Eureka, Illinois, United States
Galesburg Cottage Hospital
🇺🇸
Galesburg, Illinois, United States
Weiss Memorial Hospital
🇺🇸
Chicago, Illinois, United States
Ingalls Memorial Hospital
🇺🇸
Harvey, Illinois, United States
Mcdonough District Hospital
🇺🇸
Macomb, Illinois, United States
Decatur Memorial Hospital
🇺🇸
Decatur, Illinois, United States
Heartland Cancer Research NCORP
🇺🇸
Decatur, Illinois, United States
Proctor Hospital
🇺🇸
Peoria, Illinois, United States
Illinois CancerCare-Peoria
🇺🇸
Peoria, Illinois, United States
Kewanee Hospital
🇺🇸
Kewanee, Illinois, United States
Mason District Hospital
🇺🇸
Havana, Illinois, United States
Edward Hospital/Cancer Center
🇺🇸
Naperville, Illinois, United States
Illinois CancerCare-Galesburg
🇺🇸
Galesburg, Illinois, United States
Mayo Clinic
🇺🇸
Rochester, Minnesota, United States
Perry Memorial Hospital
🇺🇸
Princeton, Illinois, United States
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
🇺🇸
Pekin, Illinois, United States
Loyola University Medical Center
🇺🇸
Maywood, Illinois, United States
Carle Cancer Center
🇺🇸
Urbana, Illinois, United States
Community Hospital East
🇺🇸
Indianapolis, Indiana, United States
Memorial Hospital of South Bend
🇺🇸
South Bend, Indiana, United States
Physicians' Clinic of Iowa PC
🇺🇸
Cedar Rapids, Iowa, United States
Saint Luke's Hospital
🇺🇸
Cedar Rapids, Iowa, United States
Mercy Hospital
🇺🇸
Coon Rapids, Minnesota, United States
Medical Oncology and Hematology Associates-West Des Moines
🇺🇸
Clive, Iowa, United States
Cancer Center of Kansas - Dodge City
🇺🇸
Dodge City, Kansas, United States
Medical Associates Clinic PC
🇺🇸
Dubuque, Iowa, United States
Mercy Medical Center - North Iowa
🇺🇸
Mason City, Iowa, United States
Cancer Center of Kansas - Chanute
🇺🇸
Chanute, Kansas, United States
Siouxland Regional Cancer Center
🇺🇸
Sioux City, Iowa, United States
Cancer Center of Kansas - Salina
🇺🇸
Salina, Kansas, United States
Saint Francis Hospital and Medical Center - Topeka
🇺🇸
Topeka, Kansas, United States
Kaiser Permanente - Largo Medical Center
🇺🇸
Largo, Maryland, United States
Harbor Hospital Center
🇺🇸
Baltimore, Maryland, United States
Anne Arundel Medical Center
🇺🇸
Annapolis, Maryland, United States
Kaiser Permanente - Shady Grove Medical Center
🇺🇸
Rockville, Maryland, United States
Mass General/North Shore Cancer Center
🇺🇸
Danvers, Massachusetts, United States
Hickman Cancer Center
🇺🇸
Adrian, Michigan, United States
Lahey Hospital and Medical Center
🇺🇸
Burlington, Massachusetts, United States
Wayne State University/Karmanos Cancer Institute
🇺🇸
Detroit, Michigan, United States
Green Bay Oncology - Iron Mountain
🇺🇸
Iron Mountain, Michigan, United States
Meeker County Memorial Hospital
🇺🇸
Litchfield, Minnesota, United States
Cancer Research Consortium of West Michigan NCORP
🇺🇸
Grand Rapids, Michigan, United States
Mid-Michigan Medical Center - Midland
🇺🇸
Midland, Michigan, United States
Fairview Ridges Hospital
🇺🇸
Burnsville, Minnesota, United States
Saint John Macomb-Oakland Hospital
🇺🇸
Warren, Michigan, United States
Lakeland Hospital
🇺🇸
Saint Joseph, Michigan, United States
Unity Hospital
🇺🇸
Fridley, Minnesota, United States
Saint John's Hospital - Healtheast
🇺🇸
Maplewood, Minnesota, United States
Minnesota Oncology Hematology PA-Maplewood
🇺🇸
Maplewood, Minnesota, United States
Metro Minnesota Community Oncology Research Consortium
🇺🇸
Saint Louis Park, Minnesota, United States
Virginia Piper Cancer Institute
🇺🇸
Minneapolis, Minnesota, United States
Hennepin County Medical Center
🇺🇸
Minneapolis, Minnesota, United States
North Memorial Medical Health Center
🇺🇸
Robbinsdale, Minnesota, United States
Saint Francis Regional Medical Center
🇺🇸
Shakopee, Minnesota, United States
Ridgeview Medical Center
🇺🇸
Waconia, Minnesota, United States
Rice Memorial Hospital
🇺🇸
Willmar, Minnesota, United States
Keesler Medical Center
🇺🇸
Keesler Air Force Base, Mississippi, United States
Saint Anthony's Medical Center
🇺🇸
Saint Louis, Missouri, United States
Benefis Healthcare- Sletten Cancer Institute
🇺🇸
Great Falls, Montana, United States
Missouri Baptist Medical Center
🇺🇸
Saint Louis, Missouri, United States
Frisbie Hospital
🇺🇸
Rochester, New Hampshire, United States
Cooper Hospital University Medical Center
🇺🇸
Camden, New Jersey, United States
Renown Regional Medical Center
🇺🇸
Reno, Nevada, United States
New Hampshire Oncology Hematology PA-Concord
🇺🇸
Concord, New Hampshire, United States
The Cancer Institute of New Jersey Hamilton
🇺🇸
Hamilton, New Jersey, United States
Inspira Medical Center Vineland
🇺🇸
Vineland, New Jersey, United States
Kings County Hospital
🇺🇸
Brooklyn, New York, United States
Adirondack Cancer Center
🇺🇸
Glens Falls, New York, United States
Northwell Health NCORP
🇺🇸
Lake Success, New York, United States
North Shore University Hospital
🇺🇸
Manhasset, New York, United States
Long Island Jewish Medical Center
🇺🇸
New Hyde Park, New York, United States
Saint Vincent's Hospital and Medical Center of New York
🇺🇸
New York, New York, United States
Weill Medical College of Cornell University
🇺🇸
New York, New York, United States
Staten Island University Hospital
🇺🇸
Staten Island, New York, United States
Carolinas HealthCare System NorthEast
🇺🇸
Concord, North Carolina, United States
Hope Women's Cancer Centers-Asheville
🇺🇸
Asheville, North Carolina, United States
Mission Hospital-Memorial Campus
🇺🇸
Asheville, North Carolina, United States
Wayne Memorial Hospital
🇺🇸
Goldsboro, North Carolina, United States
Rutherford Hospital
🇺🇸
Rutherfordton, North Carolina, United States
Altru Hospital
🇺🇸
Grand Forks, North Dakota, United States
Sanford Bismarck Medical Center
🇺🇸
Bismarck, North Dakota, United States
Mid Dakota Clinic
🇺🇸
Bismarck, North Dakota, United States
Trinity Cancer Care Center
🇺🇸
Minot, North Dakota, United States
Toledo Clinic Cancer Centers-Bowling Green
🇺🇸
Bowling Green, Ohio, United States
Adena Regional Medical Center
🇺🇸
Chillicothe, Ohio, United States
Doctors Hospital
🇺🇸
Columbus, Ohio, United States
Case Western Reserve University
🇺🇸
Cleveland, Ohio, United States
Mount Carmel Health Center West
🇺🇸
Columbus, Ohio, United States
MetroHealth Medical Center
🇺🇸
Cleveland, Ohio, United States
Riverside Methodist Hospital
🇺🇸
Columbus, Ohio, United States
Samaritan North Health Center
🇺🇸
Dayton, Ohio, United States
Kettering Medical Center
🇺🇸
Kettering, Ohio, United States
Fairfield Medical Center
🇺🇸
Lancaster, Ohio, United States
Toledo Radiation Oncology at Northwest Ohio Onocolgy Center
🇺🇸
Maumee, Ohio, United States
Saint Charles Hospital
🇺🇸
Oregon, Ohio, United States
Licking Memorial Hospital
🇺🇸
Newark, Ohio, United States
North Coast Cancer Care
🇺🇸
Sandusky, Ohio, United States
Springfield Regional Medical Center
🇺🇸
Springfield, Ohio, United States
University of Toledo
🇺🇸
Toledo, Ohio, United States
Mercy Saint Anne Hospital
🇺🇸
Toledo, Ohio, United States
Genesis Healthcare System Cancer Care Center
🇺🇸
Zanesville, Ohio, United States
Legacy Good Samaritan Hospital and Medical Center
🇺🇸
Portland, Oregon, United States
Providence Portland Medical Center
🇺🇸
Portland, Oregon, United States
Saint Charles Medical Center-Bend
🇺🇸
Bend, Oregon, United States
Thomas Jefferson University Hospital
🇺🇸
Philadelphia, Pennsylvania, United States
Chestnut Hill Health System
🇺🇸
Philadelphia, Pennsylvania, United States
Guthrie Medical Group PC-Robert Packer Hospital
🇺🇸
Sayre, Pennsylvania, United States
Legacy Meridian Park Hospital
🇺🇸
Tualatin, Oregon, United States
Legacy Emanuel Hospital and Health Center
🇺🇸
Portland, Oregon, United States
Saint Luke's University Hospital-Bethlehem Campus
🇺🇸
Bethlehem, Pennsylvania, United States
Lehigh Valley Hospital-Cedar Crest
🇺🇸
Allentown, Pennsylvania, United States
Geisinger Medical Center
🇺🇸
Danville, Pennsylvania, United States
Penn State Hershey Cancer Institute-Clinical Trials Office
🇺🇸
Hershey, Pennsylvania, United States
Lancaster General Hospital
🇺🇸
Lancaster, Pennsylvania, United States
Saint Mary Medical and Regional Cancer Center
🇺🇸
Langhorne, Pennsylvania, United States
University of Pittsburgh Cancer Institute (UPCI)
🇺🇸
Pittsburgh, Pennsylvania, United States
Grand View Hospital
🇺🇸
Sellersville, Pennsylvania, United States
Clements University Hospital
🇺🇸
Dallas, Texas, United States
M D Anderson Cancer Center
🇺🇸
Houston, Texas, United States
Sanford Cancer Center-Oncology Clinic
🇺🇸
Sioux Falls, South Dakota, United States
Chester County Hospital
🇺🇸
West Chester, Pennsylvania, United States
WellSpan Health-York Hospital
🇺🇸
York, Pennsylvania, United States
AnMed Health Hospital
🇺🇸
Anderson, South Carolina, United States
Women and Infants Hospital
🇺🇸
Providence, Rhode Island, United States
Miriam Hospital
🇺🇸
Providence, Rhode Island, United States
Jones Clinic
🇺🇸
Germantown, Tennessee, United States
Avera Cancer Institute
🇺🇸
Sioux Falls, South Dakota, United States
Cancer Therapy and Research Center at The UT Health Science Center at San Antonio
🇺🇸
San Antonio, Texas, United States
MultiCare Auburn Medical Center
🇺🇸
Auburn, Washington, United States
Sanford USD Medical Center - Sioux Falls
🇺🇸
Sioux Falls, South Dakota, United States
Medical City Dallas Hospital
🇺🇸
Dallas, Texas, United States
Zale Lipshy University Hospital
🇺🇸
Dallas, Texas, United States
Meharry Medical College
🇺🇸
Nashville, Tennessee, United States
Covenant Medical Center-Lakeside
🇺🇸
Lubbock, Texas, United States
Central Vermont Medical Center/National Life Cancer Treatment
🇺🇸
Berlin, Vermont, United States
UT Southwestern/Simmons Cancer Center-Dallas
🇺🇸
Dallas, Texas, United States
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
🇺🇸
Houston, Texas, United States
Doctor's Hospital of Laredo
🇺🇸
Laredo, Texas, United States
University of Vermont College of Medicine
🇺🇸
Burlington, Vermont, United States
University of Texas Health Science Center at San Antonio
🇺🇸
San Antonio, Texas, United States
Scott and White Memorial Hospital
🇺🇸
Temple, Texas, United States
Sacred Heart Hospital
🇺🇸
Eau Claire, Wisconsin, United States
Cancer Care Northwest - Spokane South
🇺🇸
Spokane, Washington, United States
Saint Francis Hospital
🇺🇸
Federal Way, Washington, United States
PeaceHealth Saint Joseph Medical Center
🇺🇸
Bellingham, Washington, United States
Providence Regional Cancer System-Centralia
🇺🇸
Centralia, Washington, United States
Group Health Cooperative of Puget Sound Oncology Consortium
🇺🇸
Seattle, Washington, United States
Group Health Cooperative-Seattle
🇺🇸
Seattle, Washington, United States
Vince Lombardi Cancer Clinic-Marinette
🇺🇸
Marinette, Wisconsin, United States
CancerCare Manitoba
🇨🇦
Winnipeg, Manitoba, Canada
Marshfield Clinic-Minocqua Center
🇺🇸
Minocqua, Wisconsin, United States
Marshfield Clinic
🇺🇸
Marshfield, Wisconsin, United States
Cross Cancer Institute
🇨🇦
Edmonton, Alberta, Canada
BCCA-Vancouver Cancer Centre
🇨🇦
Vancouver, British Columbia, Canada
CHUM-Hotel Dieu du Montreal
🇨🇦
Montreal, Quebec, Canada
Doctor H. Bliss Murphy Cancer Centre
🇨🇦
St. John's, Newfoundland and Labrador, Canada
Juravinski Cancer Centre at Hamilton Health Sciences
🇨🇦
Hamilton, Ontario, Canada
Ottawa Hospital and Cancer Center-General Campus
🇨🇦
Ottawa, Ontario, Canada
Washington University School of Medicine
🇺🇸
Saint Louis, Missouri, United States
Mercy Hospital Springfield
🇺🇸
Springfield, Missouri, United States
Regions Hospital
🇺🇸
Saint Paul, Minnesota, United States
Park Nicollet Clinic - Saint Louis Park
🇺🇸
Saint Louis Park, Minnesota, United States
Saint Joseph's Hospital - Healtheast
🇺🇸
Saint Paul, Minnesota, United States
United Hospital
🇺🇸
Saint Paul, Minnesota, United States
Rose Medical Center
🇺🇸
Denver, Colorado, United States
State University of New York Downstate Medical Center
🇺🇸
Brooklyn, New York, United States
Contra Costa Regional Medical Center
🇺🇸
Martinez, California, United States
Hematology and Oncology Associates-Oakland
🇺🇸
Oakland, California, United States
Memorial Medical Center
🇺🇸
Springfield, Illinois, United States
Valley Medical Oncology Consultants-Castro Valley
🇺🇸
Castro Valley, California, United States
Marin General Hospital
🇺🇸
Greenbrae, California, United States
Tom K Lee Inc
🇺🇸
Oakland, California, United States
Stanford Cancer Institute
🇺🇸
Palo Alto, California, United States
Kaiser Permanente-Richmond
🇺🇸
Richmond, California, United States
Valley Medical Oncology Consultants
🇺🇸
Pleasanton, California, United States
Kaiser Permanente-Santa Rosa
🇺🇸
Santa Rosa, California, United States
Kaiser Permanente-Walnut Creek
🇺🇸
Walnut Creek, California, United States
Well Star Cobb Hospital
🇺🇸
Austell, Georgia, United States
John B Amos Cancer Center
🇺🇸
Columbus, Georgia, United States
Wellstar Kennestone Hospital
🇺🇸
Marietta, Georgia, United States
Memorial University Medical Center
🇺🇸
Savannah, Georgia, United States
Graham Hospital Association
🇺🇸
Canton, Illinois, United States
Lewis Cancer and Research Pavilion at Saint Joseph's/Candler
🇺🇸
Savannah, Georgia, United States
Rush University Medical Center
🇺🇸
Chicago, Illinois, United States
Bromenn Regional Medical Center
🇺🇸
Normal, Illinois, United States
Elkhart General Hospital
🇺🇸
Elkhart, Indiana, United States
Community Regional Cancer Care-North
🇺🇸
Indianapolis, Indiana, United States
IU Health Arnett Cancer Care
🇺🇸
Lafayette, Indiana, United States
Horizon Oncology Center
🇺🇸
Lafayette, Indiana, United States
Northern Indiana Cancer Research Consortium
🇺🇸
South Bend, Indiana, United States
Oncology Associates at Mercy Medical Center
🇺🇸
Cedar Rapids, Iowa, United States
Allegiance Health
🇺🇸
Jackson, Michigan, United States
Marquette General Hospital
🇺🇸
Marquette, Michigan, United States
William Beaumont Hospital-Royal Oak
🇺🇸
Royal Oak, Michigan, United States
Grant Medical Center
🇺🇸
Columbus, Ohio, United States
Aria Health-Torresdale Campus
🇺🇸
Philadelphia, Pennsylvania, United States
Western Oncology Research Consortium
🇺🇸
Portland, Oregon, United States
Allegheny General Hospital
🇺🇸
Pittsburgh, Pennsylvania, United States
Geisinger Medical Group
🇺🇸
State College, Pennsylvania, United States
Saint Clare Hospital
🇺🇸
Lakewood, Washington, United States
Kaiser Permanente - Fair Oaks Medical Center
🇺🇸
Fairfax, Virginia, United States
Fredericksburg Oncology Inc
🇺🇸
Fredericksburg, Virginia, United States
Providence - Saint Peter Hospital
🇺🇸
Olympia, Washington, United States
Swedish Medical Center-First Hill
🇺🇸
Seattle, Washington, United States
Northwest NCI Community Oncology Research Program
🇺🇸
Tacoma, Washington, United States
Midelfort Clinic-Clairemont Campus
🇺🇸
Eau Claire, Wisconsin, United States
Langlade Hospital and Cancer Center
🇺🇸
Antigo, Wisconsin, United States
Green Bay Oncology at Saint Vincent Hospital
🇺🇸
Green Bay, Wisconsin, United States
Saint Vincent Hospital
🇺🇸
Green Bay, Wisconsin, United States
Green Bay Oncology Limited at Saint Mary's Hospital
🇺🇸
Green Bay, Wisconsin, United States
Saint Mary's Hospital
🇺🇸
Green Bay, Wisconsin, United States
Aurora BayCare Medical Center
🇺🇸
Green Bay, Wisconsin, United States
Gundersen Lutheran Medical Center
🇺🇸
La Crosse, Wisconsin, United States
Aspirus Regional Cancer Center
🇺🇸
Wausau, Wisconsin, United States
Bay Area Medical Center
🇺🇸
Marinette, Wisconsin, United States
Colorado Cancer Research Program NCORP
🇺🇸
Denver, Colorado, United States
Mercy General Hospital
🇺🇸
Sacramento, California, United States
Kaiser Permanente-South Sacramento
🇺🇸
Sacramento, California, United States
Kaiser Permanente - Sacramento
🇺🇸
Sacramento, California, United States
The Medical Center of Aurora
🇺🇸
Aurora, Colorado, United States
Suburban Hospital
🇺🇸
Bethesda, Maryland, United States
Saint Joseph Mercy Hospital
🇺🇸
Ann Arbor, Michigan, United States
Michigan Cancer Research Consortium NCORP
🇺🇸
Ann Arbor, Michigan, United States
University of Michigan Comprehensive Cancer Center
🇺🇸
Ann Arbor, Michigan, United States
Novant Health Forsyth Medical Center
🇺🇸
Winston-Salem, North Carolina, United States
Medical Consultants Limited
🇺🇸
Milwaukee, Wisconsin, United States
Kaiser Permanente-Redwood City
🇺🇸
Redwood City, California, United States
IU Health La Porte Hospital
🇺🇸
La Porte, Indiana, United States
Kaiser Permanente-Roseville
🇺🇸
Roseville, California, United States
MultiCare Good Samaritan Hospital
🇺🇸
Puyallup, Washington, United States
Roswell Park Cancer Institute
🇺🇸
Buffalo, New York, United States
University Hospital of Brooklyn
🇺🇸
Brooklyn, New York, United States
Saint Joseph Regional Medical Center - Mishawaka
🇺🇸
Mishawaka, Indiana, United States
Brookdale Hospital Medical Center
🇺🇸
Brooklyn, New York, United States
Geisinger Wyoming Valley/Henry Cancer Center
🇺🇸
Wilkes-Barre, Pennsylvania, United States
Louisiana State University Health Sciences Center Shreveport
🇺🇸
Shreveport, Louisiana, United States
Providence Alaska Medical Center
🇺🇸
Anchorage, Alaska, United States
Valley Medical Oncology Consultants-Fremont
🇺🇸
Fremont, California, United States
Mayo Clinic in Arizona
🇺🇸
Scottsdale, Arizona, United States
Palo Alto Medical Foundation-Camino Division
🇺🇸
Mountain View, California, United States
Palo Alto Medical Foundation Health Care
🇺🇸
Palo Alto, California, United States
Mercy Regional Cancer Center
🇺🇸
Redding, California, United States
Kaiser Permanente-San Rafael
🇺🇸
San Rafael, California, United States
Penrose-Saint Francis Healthcare
🇺🇸
Colorado Springs, Colorado, United States
Boulder Community Hospital
🇺🇸
Boulder, Colorado, United States
Saint Anthony Hospital
🇺🇸
Lakewood, Colorado, United States
Sky Ridge Medical Center
🇺🇸
Lone Tree, Colorado, United States
Longmont United Hospital
🇺🇸
Longmont, Colorado, United States
Eastern Connecticut Hematology and Oncology Associates
🇺🇸
Norwich, Connecticut, United States
Mount Sinai Medical Center
🇺🇸
Miami Beach, Florida, United States
Florida Cancer Specialists - Sarasota Downtown
🇺🇸
Sarasota, Florida, United States
Mayo Clinic in Florida
🇺🇸
Jacksonville, Florida, United States
Memorial Regional Hospital/Joe DiMaggio Children's Hospital
🇺🇸
Hollywood, Florida, United States
Emory University/Winship Cancer Institute
🇺🇸
Atlanta, Georgia, United States
Harbin Clinic Medical Oncology and Clinical Research
🇺🇸
Rome, Georgia, United States
Southern Regional Medical Center
🇺🇸
Riverdale, Georgia, United States
Sarah Culbertson Memorial Hospital
🇺🇸
Rushville, Illinois, United States
Pekin Hospital
🇺🇸
Pekin, Illinois, United States
Western Illinois Cancer Treatment Center
🇺🇸
Galesburg, Illinois, United States
Community Cancer Center Foundation
🇺🇸
Normal, Illinois, United States
Methodist Medical Center of Illinois
🇺🇸
Peoria, Illinois, United States
OSF Saint Anthony Medical Center
🇺🇸
Rockford, Illinois, United States
Hopedale Medical Complex - Hospital
🇺🇸
Hopedale, Illinois, United States
Saint Margaret's Hospital
🇺🇸
Spring Valley, Illinois, United States
Fort Wayne Medical Oncology and Hematology Inc-Parkview
🇺🇸
Fort Wayne, Indiana, United States
McFarland Clinic PC-William R Bliss Cancer Center
🇺🇸
Ames, Iowa, United States
Genesis Medical Center - East Campus
🇺🇸
Davenport, Iowa, United States
Wichita NCI Community Oncology Research Program
🇺🇸
Wichita, Kansas, United States
Eastern Maine Medical Center
🇺🇸
Bangor, Maine, United States
Union Hospital of Cecil County
🇺🇸
Elkton, Maryland, United States
Cancer Center of Kansas - Winfield
🇺🇸
Winfield, Kansas, United States
MetroWest Medical Center-Framingham Union Hospital
🇺🇸
Framingham, Massachusetts, United States
Bixby Medical Center
🇺🇸
Adrian, Michigan, United States
Emerson Hospital/MGH Cancer Center
🇺🇸
Concord, Massachusetts, United States
Lowell General Hospital
🇺🇸
Lowell, Massachusetts, United States
South Shore Hospital
🇺🇸
South Weymouth, Massachusetts, United States
Newton-Wellesley Hospital
🇺🇸
Newton, Massachusetts, United States
Green Bay Oncology - Escanaba
🇺🇸
Escanaba, Michigan, United States
Genesys Regional Medical Center-West Flint Campus
🇺🇸
Flint, Michigan, United States
Mercy Memorial Hospital
🇺🇸
Monroe, Michigan, United States
Saint Mary's of Michigan
🇺🇸
Saginaw, Michigan, United States
Toledo Clinic Cancer Centers-Monroe
🇺🇸
Monroe, Michigan, United States
Fairview-Southdale Hospital
🇺🇸
Edina, Minnesota, United States
Essentia Health Cancer Center
🇺🇸
Duluth, Minnesota, United States
Hutchinson Area Health Care
🇺🇸
Hutchinson, Minnesota, United States
Minnesota Oncology and Hematology PA-Woodbury
🇺🇸
Woodbury, Minnesota, United States
Woodwinds Health Campus
🇺🇸
Woodbury, Minnesota, United States
Montana Cancer Consortium NCORP
🇺🇸
Billings, Montana, United States
Benefis Healthcare-West Campus
🇺🇸
Great Falls, Montana, United States
Great Falls Clinic
🇺🇸
Great Falls, Montana, United States
Nebraska Methodist Hospital
🇺🇸
Omaha, Nebraska, United States
Exeter Hospital
🇺🇸
Exeter, New Hampshire, United States
New Hampshire Oncology Hematology PA-Hooksett
🇺🇸
Hooksett, New Hampshire, United States
Cheshire Medical Center-Dartmouth-Hitchcock Keene
🇺🇸
Keene, New Hampshire, United States
Dartmouth Hitchcock Medical Center
🇺🇸
Lebanon, New Hampshire, United States
Elliot Hospital
🇺🇸
Manchester, New Hampshire, United States
Monmouth Medical Center
🇺🇸
Long Branch, New Jersey, United States
Morristown Medical Center
🇺🇸
Morristown, New Jersey, United States
Virtua Voorhees
🇺🇸
Voorhees, New Jersey, United States
Virtua Memorial
🇺🇸
Mount Holly, New Jersey, United States
Rutgers Cancer Institute of New Jersey
🇺🇸
New Brunswick, New Jersey, United States
Cone Health Cancer Center at Alamance Regional
🇺🇸
Burlington, North Carolina, United States
FirstHealth of the Carolinas-Moore Regional Hosiptal
🇺🇸
Pinehurst, North Carolina, United States
Southeast Clinical Oncology Research (SCOR) Consortium NCORP
🇺🇸
Winston-Salem, North Carolina, United States
Aultman Health Foundation
🇺🇸
Canton, Ohio, United States
Ohio State University Comprehensive Cancer Center
🇺🇸
Columbus, Ohio, United States
Columbus NCI Community Oncology Research Program
🇺🇸
Columbus, Ohio, United States
Grady Memorial Hospital
🇺🇸
Delaware, Ohio, United States
Miami Valley Hospital
🇺🇸
Dayton, Ohio, United States
Dayton NCI Community Oncology Research Program
🇺🇸
Dayton, Ohio, United States
Atrium Medical Center-Middletown Regional Hospital
🇺🇸
Franklin, Ohio, United States
Marietta Memorial Hospital
🇺🇸
Marietta, Ohio, United States
Toledo Clinic Cancer Centers-Oregon
🇺🇸
Oregon, Ohio, United States
Toledo Clinic Cancer Centers-Maumee
🇺🇸
Maumee, Ohio, United States
Lima Memorial Hospital
🇺🇸
Lima, Ohio, United States
The Toledo Hospital/Toledo Children's Hospital
🇺🇸
Toledo, Ohio, United States
Saint Vincent Mercy Medical Center
🇺🇸
Toledo, Ohio, United States
Toledo Clinic Cancer Centers-Toledo
🇺🇸
Toledo, Ohio, United States
Toledo Community Hospital Oncology Program CCOP
🇺🇸
Toledo, Ohio, United States
Cleveland Clinic Wooster Family Health and Surgery Center
🇺🇸
Wooster, Ohio, United States
Fulton County Health Center
🇺🇸
Wauseon, Ohio, United States
Saint Ann's Hospital
🇺🇸
Westerville, Ohio, United States
Greene Memorial Hospital
🇺🇸
Xenia, Ohio, United States
Tod Children's Hospital - Forum Health
🇺🇸
Youngstown, Ohio, United States
Bend Memorial Clinic
🇺🇸
Bend, Oregon, United States
Legacy Mount Hood Medical Center
🇺🇸
Gresham, Oregon, United States
Providence Milwaukie Hospital
🇺🇸
Milwaukie, Oregon, United States
Geisinger Medical Center-Cancer Center Hazleton
🇺🇸
Hazleton, Pennsylvania, United States
Lewistown Hospital
🇺🇸
Lewistown, Pennsylvania, United States
University of Pennsylvania/Abramson Cancer Center
🇺🇸
Philadelphia, Pennsylvania, United States
Mount Nittany Medical Center
🇺🇸
State College, Pennsylvania, United States
Scranton Hematology Oncology
🇺🇸
Scranton, Pennsylvania, United States
Spartanburg Medical Center
🇺🇸
Spartanburg, South Carolina, United States
Thompson Cancer Survival Center
🇺🇸
Knoxville, Tennessee, United States
Nashville Oncology Associates PC
🇺🇸
Nashville, Tennessee, United States
Erlanger Medical Center
🇺🇸
Chattanooga, Tennessee, United States
Edwards Comprehensive Cancer Center
🇺🇸
Huntington, West Virginia, United States
PeaceHealth Southwest Medical Center
🇺🇸
Vancouver, Washington, United States
Southwestern Vermont Medical Center
🇺🇸
Bennington, Vermont, United States
Aurora Cancer Care-Southern Lakes
🇺🇸
Elkhorn, Wisconsin, United States
Holy Family Memorial Hospital
🇺🇸
Manitowoc, Wisconsin, United States
Green Bay Oncology - Sturgeon Bay
🇺🇸
Sturgeon Bay, Wisconsin, United States
Green Bay Oncology - Oconto Falls
🇺🇸
Oconto Falls, Wisconsin, United States
Penticton Regional Hospital
🇨🇦
Penticton, British Columbia, Canada
BCCA-Fraser Valley Cancer Centre
🇨🇦
Surrey, British Columbia, Canada
Cancer Centre of Southeastern Ontario at Kingston General Hospital
🇨🇦
Kingston, Ontario, Canada
London Regional Cancer Program
🇨🇦
London, Ontario, Canada
Health Sciences North
🇨🇦
Sudbury, Ontario, Canada
CSSS Champlain-Charles Le Moyne
🇨🇦
Greenfield Park, Quebec, Canada
Thunder Bay Regional Health Science Centre
🇨🇦
Thunder Bay, Ontario, Canada
International Breast Cancer Study Group
🇨🇭
Bern, Switzerland
UNC Lineberger Comprehensive Cancer Center
🇺🇸
Chapel Hill, North Carolina, United States
Tom Baker Cancer Centre
🇨🇦
Calgary, Alberta, Canada
Swedish Medical Center
🇺🇸
Englewood, Colorado, United States
Norwalk Hospital
🇺🇸
Norwalk, Connecticut, United States
Stamford Hospital/Bennett Cancer Center
🇺🇸
Stamford, Connecticut, United States
Bayhealth Medical Center at Kent General
🇺🇸
Dover, Delaware, United States
Beebe Medical Center
🇺🇸
Lewes, Delaware, United States
Nanticoke Memorial Hospital
🇺🇸
Seaford, Delaware, United States
Christiana Care Health System-Christiana Hospital
🇺🇸
Newark, Delaware, United States
Memorial Hospital
🇺🇸
Chattanooga, Tennessee, United States
Kaiser Permanente - Towson Medical Center
🇺🇸
Lutherville, Maryland, United States
Memorial Sloan-Kettering Cancer Center
🇺🇸
New York, New York, United States
Fox Chase Cancer Center
🇺🇸
Philadelphia, Pennsylvania, United States
Avera McKennan Hospital and University Health Center
🇺🇸
Sioux Falls, South Dakota, United States
Medical X-Ray Center
🇺🇸
Sioux Falls, South Dakota, United States
Allan Blair Cancer Centre
🇨🇦
Regina, Saskatchewan, Canada
Hopital Du Sacre-Coeur de Montreal
🇨🇦
Montreal, Quebec, Canada
BCCA-Cancer Centre for the Southern Interior
🇨🇦
Kelowna, British Columbia, Canada
Tripler Army Medical Center
🇺🇸
Honolulu, Hawaii, United States
Mercy Capitol
🇺🇸
Des Moines, Iowa, United States
Iowa Methodist Medical Center
🇺🇸
Des Moines, Iowa, United States
Iowa-Wide Oncology Research Coalition NCORP
🇺🇸
Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Des Moines
🇺🇸
Des Moines, Iowa, United States
Medical Oncology and Hematology Associates-Laurel
🇺🇸
Des Moines, Iowa, United States
Montefiore Medical Center-Weiler Hospital
🇺🇸
Bronx, New York, United States
Montefiore Medical Center - Moses Campus
🇺🇸
Bronx, New York, United States
Virginia Commonwealth University/Massey Cancer Center
🇺🇸
Richmond, Virginia, United States
UW Health Oncology-One South Park
🇺🇸
Madison, Wisconsin, United States
Dean Hematology and Oncology Clinic
🇺🇸
Madison, Wisconsin, United States
University of Wisconsin Hospital and Clinics
🇺🇸
Madison, Wisconsin, United States
Presbyterian Kaseman Hospital
🇺🇸
Albuquerque, New Mexico, United States
University of New Mexico Cancer Center
🇺🇸
Albuquerque, New Mexico, United States
Hematology Oncology Associates
🇺🇸
Albuquerque, New Mexico, United States
Good Samaritan Hospital - Dayton
🇺🇸
Dayton, Ohio, United States
Associates In Womens Health
🇺🇸
Wichita, Kansas, United States
Baptist MD Anderson Cancer Center
🇺🇸
Jacksonville, Florida, United States
MultiCare Allenmore Hospital
🇺🇸
Tacoma, Washington, United States
Multicare Health System
🇺🇸
Tacoma, Washington, United States
OSF Saint Francis Medical Center
🇺🇸
Peoria, Illinois, United States
Ottawa Regional Hospital and Healthcare Center
🇺🇸
Ottawa, Illinois, United States
Illinois Valley Hospital
🇺🇸
Peru, Illinois, United States
Valley Radiation Oncology
🇺🇸
Peru, Illinois, United States
Cancer Center of Kansas - McPherson
🇺🇸
McPherson, Kansas, United States
Rhode Island Hospital
🇺🇸
Providence, Rhode Island, United States