Effects of early luteal phase estrogen and progesterone administration on luteolysis in normo-ovulatory women.
Completed
- Conditions
- The study will performed in healthy volunteers in order to get more insight in the mechanisms behind the insufficient luteal phase in patients treated with ovarian hyperstimulation for IVF.
- Registration Number
- NL-OMON22980
- Lead Sponsor
- . Beckers, fertiliteitsarts, Room Hs 423, dr. Molewaterplein 40, 3015 GD Rotterdam. Tel: 010-4635738Partially sponsored by Pantharhei
- Brief Summary
Eur J Endocrinol. 2006 Aug;155(2):355-63.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Regular menstrual cycle (25-34 days);
2. normal body weight (BMI 18-28);
Exclusion Criteria
1. Known or suspected pregnancy;
2. the use of oral contraceptives (i.e. Provera®, Mirena®, Nuva ring® ect.) in the last three months;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Duration of the luteal phase. Every subject will undergo an end of trial visit. In this visit the subjects will hand over a paper on wich she will write down the onset of the menstuation. These data will be put into a excel database.
- Secondary Outcome Measures
Name Time Method Endocrine profiles. Blood will be sampled every other day in the luteal phase from the day of the positive LH test until day LH+14.