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临床试验/NCT06095609
NCT06095609已完成不适用

The Implementation of Early Mobilization and Chest Physiotherapy on Weaning Rate of Prolong Weaning Patients. A Retrospective Study

Taoyuan General Hospital2 个研究点 分布在 1 个国家目标入组 202 人开始时间: 2022年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
202
试验地点
2
主要终点
Weaning success rate

研究概览

简要总结

Weaning from mechanical ventilator is essential to liberate patients to normal life. Prolong weaning is defined as failure of 3 times spontaneous breath trial (SBT) and requiring more than 7 days weaning from mechanical ventilation after first SBT. higher unsuccessful rate of extubation and higher mortality rate. Possible reasons to cause prolong weaning could be attributed to intensive care unit acquired weakness (ICU-AW) and poor lung hygiene. In order to solve these two problems and increase the weaning rate, early mobilization (EM) and chest physiotherapy (CPT) are considered as possible strategy to attain the goal. According to previous articles, lacking of control group and small sample size made it difficult to confirm the true effect of EM and CPT on prolong weaning patients. Thus, the aims of this articles are discussing the influence from EM with CPT on weaning rate and other hospitalization outcomes with larger sample sizes and control group.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
20 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • The subjects' data which met the inclusion criteria are:
  • Patient with or without
  • Patient who met the criteria of received physiotherapy (Figure 1.)
  • No usage of life support device such as ECMO and so on.
  • Continuous mechanical ventilator use over 21 days.

排除标准

  • The exclusion criteria are
  • Patients diagnosed as brain death
  • Patients who were ventilator dependent before admission
  • Patients who were against advice discharge under critical condition.
  • Patients received emergency intervention during course.
  • Patient who didn't meet the criteria of received physiotherapy (Figure 1.).

结局指标

主要结局

Weaning success rate

时间窗: up to 6 weeks in respiratory care center

Weaning success was defined as patients being free from MV or BiPAP for 5 days based on Taiwan

次要结局

  • RCC mortality rate(up to 6 weeks in respiratory care center)
  • discharge to home rate(after 6 weeks in respiratory care center)
  • hospital mortality rate(up to 6 weeks in respiratory care center)
  • total mechanical ventilator use(up to 6 weeks in respiratory care center)
  • total hospital days of stay(up to 10 weeks in the hospital)
  • RCC days of stay(up to 6 weeks in respiratory care center)

研究者

发起方
Taoyuan General Hospital
申办方类型
Other Gov
责任方
Sponsor

研究点 (2)

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