Etiological Diagnosis of Urinary Stone in Chinese Children
试验速览
- 阶段
- 不适用
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Urinary oxalate;
研究概览
简要总结
The incidence of nephrolithiasis in children has been reported to increase by approximately 6-10% annually, and the incidence is currently 50 per 100,000 children with high recurrent rate. Investigators aimed to determine the metabolic risk factors in Chinese children through metabolic evaluation.
In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.
详细描述
Investigators aimed to determine the metabolic risk factors in 200 Chinese children with urinary stones through metabolic evaluation.
In order to identify diagnostic criteria of hypocitraturia and hyperoxaluria in western country wether adapt to Chinese children, investigators aim to determine normal urine levels of oxalate and citrate in children without kidney stone.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 16 Years（Child）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Children with urinary stones
排除标准
- •Anatomic urinary system abnormality, vesicoureteral reflux, urinary tract infection (temperature >38°C and/or positive urine culture), solitary kidney, and renal insufficiency
结局指标
主要结局
Urinary oxalate;
时间窗: urine collected in 24 hours
次要结局
- Urinary citrate;(urine collected in 24 hours)
- Urinary calcium(urine collected in 24 hours)
研究者
Hongquan Geng
Director, Department of Pediatric Urology
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine