NCT02276573已完成不适用
Study of Inflammatory Role of Epstein-Barr Virus (EBV) in Atrophic and Erosive Forms of Oral Lichen Planus
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 13
- 试验地点
- 1
- 主要终点
- Measure of level of EBV nucleic acids
研究概览
简要总结
Oral lichen planus (OLP) is a chronic inflammatory and relapsing. The average prevalence is 1 to 4%. The clinics forms are many and symptoms are varied. The erosive form, painful and debilitating is characterized by erosive areas, ulcerated on an erythematous base with or without a keratinocyte lichenien network.
The literature data moving towards an autoimmune origin, but the pathophysiological mechanisms of OLP remain unknown.
This project represents the first part of a comprehensive project to examine the oral pathogenesis of different viruses (Herpes and papillomavirus HPV) and centered on Epstein-Barr Virus (EBV).
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patient ≥ 18 years
- •Clinical and/or histological diagnosis of erosive or atrophic OLP
- •No signs of severe dysplasia at the sampling
排除标准
- •o immunosuppressive or anti-inflammatory therapies at the inclusion
结局指标
主要结局
Measure of level of EBV nucleic acids
时间窗: day 1
次要结局
未报告次要终点
研究者
研究点 (1)
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