ACTRN12618000411246
Completed
未知
A nurse lead intervention to reduce delirium among adults admitted to intensive care: a randomised multi-centre step-wedged study.
iverpool Hospital0 sites2,618 target enrollmentMarch 21, 2018
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Delirium
- Sponsor
- iverpool Hospital
- Enrollment
- 2618
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Delirium is an acute change in behaviour characterised by a fluctuating level of consciousness with impaired attention and cognition. For critically ill adults the incidence of delirium is approximately 30%. The objective of this study is to determine the effectiveness of a nurse-led delirium-prevention protocol in reducing the incidence, severity, and duration of delirium among adults admitted to intensive care. Between May 2019 and February 2021, 2,618 admissions, among 2,566 patients were included in the study. Following the introduction of a nurse-led, non-pharmacological bundle of care to prevent delirium, among adults admitted to intensive care, we observed no significant decrease in the incidence of delirium, or the duration of delirium.
Investigators
Eligibility Criteria
Inclusion Criteria
- •All adults aged 18 years or more admitted to the intensive care during the study period.
Exclusion Criteria
- •(1\) patients at the end\-of\-life, and not expected to survive 24 hours; (2\) patients not expected to stay in the ICU for at least 24 hours; (3\) patients with acute or chronic neurological conditions that prevented assessment of delirium (traumatic brain injury, intra\-cerebral hemorrhage, ischaemic stroke, CNS infection, hypoxic brain injury, hepatic encephalopathy, severe mental disability, serious receptive aphasia, dementia).
Outcomes
Primary Outcomes
Not specified
Similar Trials
Unknown
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Pharmacological treatment of organic psychosis in critically ill adultsDelirium state in critical ill patientsMedDRA version: 21.0Level: LLTClassification code 10071313Term: Hypoactive deliriumSystem Organ Class: 100000004873MedDRA version: 21.0Level: LLTClassification code 10012226Term: Delirium, cause unknownSystem Organ Class: 100000004873MedDRA version: 21.0Level: LLTClassification code 10012220Term: Delirium due to a general medical conditionSystem Organ Class: 100000004873MedDRA version: 21.1Level: LLTClassification code 10042275Term: Subacute deliriumSystem Organ Class: 100000004873MedDRA version: 21.1Level: LLTClassification code 10013758Term: Drug-induced deliriumSystem Organ Class: 100000004873MedDRA version: 21.1Level: LLTClassification code 10000702Term: Acute deliriumSystem Organ Class: 100000004873MedDRA version: 21.0Level: LLTClassification code 10071314Term: Hyperactive deliriumSystem Organ Class: 100000004873Therapeutic area: Diseases [C] - Nervous System Diseases [C10]EUCTR2017-003829-15-ITZEALAND UNIVERSITY HOSPITAL (ERLAND PEDERSEN)1,000
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Pharmacological treatment of organic psychosis in critically ill adultsTreatment of delirium in critically ill adult patients in intensive care unit.MedDRA version: 21.1 Level: LLT Classification code 10000702 Term: Acute delirium System Organ Class: 100000004873MedDRA version: 21.1 Level: LLT Classification code 10013758 Term: Drug-induced delirium System Organ Class: 100000004873MedDRA version: 21.1 Level: LLT Classification code 10042275 Term: Subacute delirium System Organ Class: 100000004873MedDRA version: 21.0 Level: LLT Classification code 10012220 Term: Delirium due to a general medical condition System Organ Class: 100000004873MedDRA version: 21.0 Level: LLT Classification code 10012226 Term: Delirium, cause unknown System Organ Class: 100000004873MedDRA version: 20.0 Level: LLT Classification code 10050233 Term: Delirium on emergence System Organ Class: 100000004863MedDRA version: 21.0 Level: LLT Classification code 10071313 Term: Hypoactive delirium System Organ Class: 100000004873MedDRA version: 21.0 Level: LLT Classification code 10071314 Term: Hyperactive delirium System Organ Class: 100000004873MedDRA version: 21.0 Level: LLT Classification code 10071315 Term: Mixed deliriumTherapeutic area: Diseases [C] - Nervous System Diseases [C10]EUCTR2017-003829-15-ESZealand University Hospital1,000
Completed
Not Applicable
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