A nurse led intervention to prevent delirium among adults admitted to Intensive Care,

Not Applicable

Completed

• Conditions: Delirium; Neurological - Other neurological disorders

• Registration Number: ACTRN12618000411246
• Lead Sponsor: iverpool Hospital

Brief Summary

Delirium is an acute change in behaviour characterised by a fluctuating level of consciousness with impaired attention and cognition. For critically ill adults the incidence of delirium is approximately 30%. The objective of this study is to determine the effectiveness of a nurse-led delirium-prevention protocol in reducing the incidence, severity, and duration of delirium among adults admitted to intensive care. Between May 2019 and February 2021, 2,618 admissions, among 2,566 patients were included in the study. Following the introduction of a nurse-led, non-pharmacological bundle of care to prevent delirium, among adults admitted to intensive care, we observed no significant decrease in the incidence of delirium, or the duration of delirium.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2018-03-21
• Study Completion: 2020-02-29
• Last Update Posted: 9 October 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 2618

Inclusion Criteria

All adults aged 18 years or more admitted to the intensive care during the study period.

Exclusion Criteria

(1) patients at the end-of-life, and not expected to survive 24 hours; (2) patients not expected to stay in the ICU for at least 24 hours; (3) patients with acute or chronic neurological conditions that prevented assessment of delirium (traumatic brain injury, intra-cerebral hemorrhage, ischaemic stroke, CNS infection, hypoxic brain injury, hepatic encephalopathy, severe mental disability, serious receptive aphasia, dementia).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Incidence of delirium will assessed using the ICU-CAM scale, which categorising patients as CAM +ve, CAM -ve for delirium, or un-assessable due to coma.[ within first 28-days in the intensive care, each patient will be assigned CAM -ve or CAM +ve for delirium during the daily morning medical round.]

Secondary Outcome Measures

Name	Time	Method
Along with the identification of the primary outcomes of the incidence of delirium during first 28-days in the intensive car, each patient's daily CAM result will determine a delirium or delirium free day. [ The calculation of cumulative delirium free days for each patient will be undertaken at the time of discharge. ]