Pre-operative CT scan in breast conserving therapy for more accurate radiation boost volume delineation.

• Conditions: breastcancer; cancer of the breast; 10006291

• Registration Number: NL-OMON35059
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

cT1-3N0 breastcancer, calculated creatinine clearance > 60 ml/liter (Cockroft) , informed consent

Exclusion Criteria

post operative mastitis or wounddefect, contra indication for iv.contrast, neo adjuvant systemic treatment

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary: Difference in position of the pre-operative tumour on CT and<br /><br>postoperative reconstruction of the tumour-location using current standard<br /><br>information: *GTVsim* en GTVpre<br /><br><br /><br>Difference in position of the radiotherapy boost by using the pre- operative CT<br /><br>scan, compared with the postoperative simulation CT scan: CTVsim en CTVpre<br /><br><br /><br>Difference in volume of CTVsim en CTVpre</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary: Change of contour of the breast after surgery<br /><br><br /><br>Decreasing the interobserver delineation on CTVpre compared to CTVsim between<br /><br>the 4 observers</p><br>