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Clinical Trials/NCT06367192
NCT06367192
Recruiting
N/A

School Readiness Intervention for Preschool Children With Sickle Cell Disease

St. Jude Children's Research Hospital2 sites in 1 country36 target enrollmentMarch 31, 2025

Overview

Phase
N/A
Intervention
The adapted Kids in Transition to School Intervention
Conditions
Sickle Cell Disease
Sponsor
St. Jude Children's Research Hospital
Enrollment
36
Locations
2
Primary Endpoint
Feasibility of Intervention Measure
Status
Recruiting
Last Updated
8 days ago

Overview

Brief Summary

The study participant is being asked to take part in this clinical trial, a type of research study, because the participant is a young child with sickle cell disease or the caregiver of a child with sickle cell disease. This study is being done to test a school readiness program for children with sickle cell disease (ages 3.5-6,5 years old).

Primary Objective

Assess feasibility and acceptability of an adapted school readiness intervention among preschool children (ages 3.5-6.5) diagnosed with sickle cell disease.

Secondary Objectives

Objective 1:

Measure preliminary efficacy of the adapted school readiness intervention compared to routine care among preschool children ages (3.5-6.5) diagnosed with sickle cell disease.

Objective 2:

Examine implementation factors (i.e., barriers and facilitators) during post-intervention.

Detailed Description

* Group randomization- Parent and child will be randomly selected (like the flip of a coin) to receive either the school readiness intervention or the standard school resources. * Attend virtual classroom program sessions- If the participant is in the school readiness group, the caregiver, will attend about 8 weeks of sessions virtually with a teacher and a caregiver of a child with sickle cell, for a total of 8 sessions. The sessions will be during the summer and done in a group. Each session will last about 1 ½ hours and will be video recorded. These sessions will be shared with another researcher for feedback and consistency. * Complete a caregiver interview-If you are in the school readiness group, a member of the study team will interview you after the virtual classroom sessions are over. The interview will take about 15-20 minutes and will be audio recorded. The caregiver will be asked for suggestions and how satisfied with the program. * Complete assessments - Caregiver and child will complete a set of assessments that evaluate school readiness skills (e.g., early math and reading), child behaviors, and parent-child relationships before and after the intervention.

Registry
clinicaltrials.gov
Start Date
March 31, 2025
End Date
October 1, 2028
Last Updated
8 days ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosed with sickle cell disease of any genotype.
  • Enrolled on the institutional protocol: Sickle Cell Clinical Research Intervention Program (SCCRIP)
  • Age 3.5-6.5 years inclusive at the time of enrollment
  • English as the primary language
  • Research participant and one parent willing to participate and provide consent/assent according to institutional guidelines
  • Caregiver Participants
  • Have a child diagnosed with SCD of any genotype between the ages of 3.5-6.5 years and enrolled in SCCRIP
  • English as the primary language

Exclusion Criteria

  • Do not have a child diagnosed with SCD of any genotype between the ages of 3.5-6.5 years and enrolled in SCCRIP
  • Non-English speakers

Arms & Interventions

Readiness Intervention

* Attend virtual classroom program sessions- If participants are in the school readiness group, the caregiver, will attend about 8 weeks of sessions virtually with a teacher or social worker and a caregiver of a child with sickle cell, for a total of 8 sessions. The sessions will be during the summer and done in a group. Each session will last about 1 ½ hours and will be video recorded. \> •Complete a caregiver interview-If participants are in the school readiness group, a member of the study team will interview you after the virtual classroom sessions are over. The interview will take about 15-20 minutes and will be audio recorded. Participants will be asked for suggestions and how satisfied you were with the program. * Complete assessments - Caregiver and participant will complete a set of assessments that evaluate school readiness skills (e.g., early math and reading), child behaviors, and parent-child relationships before and after the intervention.

Intervention: The adapted Kids in Transition to School Intervention

Control: Standard school resources

Parents will be provided with information about preschool programs available in the community and age appropriate books for their children

Intervention: Standard school resources

Outcomes

Primary Outcomes

Feasibility of Intervention Measure

Time Frame: Collected immediately after the intervention

A brief (4-items) Likert-scale questionnaire assessing feasibility of the intervention. This measure is completed by care givers and intervention providers.

Acceptability of Intervention Measure

Time Frame: Collected immediately after the intervention

A brief (4-items) Likert-scale questionnaire assessing acceptability of the intervention. This measure is completed by care givers and intervention providers.

Secondary Outcomes

  • Bracken School Readiness Assessment - 3rd Edition(Baseline and Collected immediately after the intervention)
  • Woodcock Johnson Tests of Achievement - Fourth Edition(Baseline and Collected immediately after the intervention)
  • NIH Toolbox Flanker Test(Baseline and Collected immediately after the intervention)
  • Head-Toes-Knees-Shoulders Revised(Baseline and Collected immediately after the intervention)
  • The Parenting Scale(Baseline and Collected immediately after the intervention)
  • Behavior Rating Inventory of Executive Functioning Preschool or Child(Baseline and Collected immediately after the intervention)

Study Sites (2)

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