Effect of Kanchnar with Shunthi(Dry ginger) oral medication and Nasal therapy of Nimb tail in Hypothyroidism

Phase 3

Completed

• Conditions: Hypothyroidism, unspecified. Ayurveda Condition: GALAGANDAH,

• Registration Number: CTRI/2021/04/033150
• Lead Sponsor: GOVERNMENT PG AYURVEDA COLLEGE AND HOSPITAL VARANASI

Brief Summary

This Study is a Interventional open andrandomized, group study trial  the efficacy of Kanchnar twak kwath with shunthi churna and Nimb tail Nasya in Hypothyroidism.Patients will be randomly selected from OPD and IPD of Department of Kayachikitsa and Panchakarma, Government PG Ayurveda College and Hospital, Varanasi.

60 Patients will be studied under 2 groups having 30 patients in each group:

Group 1: 50 ml Kanchnar twak kwath with 1gm Shunthi churna two times in a day before meal.

Group 2: 50mL  kanchnar twak kwath with 1 gm Shunthi churna two times in a day before meal and 2 drops Nimb tail Nasya in each nostril.

15 days Follow up for symptoms and monthly follow up for Thyroid function test will be done in each group.

Detailed Description

Not available

Study Timeline

• Study Start: 2021-04-05
• Study Completion: 2022-05-20
• Last Update Posted: 2022-08-23

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Patients who are newly diagnosed case of Hypothyroidism with increased TSH level. TSH level > 4.5µIU/ml. Total serum T4 level less than normal value(total serum T4.
• 4.5 to 12.5µg/dl) Total serum T3 level less than normal value(total serum T3.
• 80 to 220 ng/dl) Patients having clinical features of Hypothyroidism; Puffiness of the face and eyelids, Peripheral edema etc.

Exclusion Criteria

• Patients who have under gone any type of thyroid surgery.
• Patients whose symptoms are worsely aggravated after leaving the modern drug Levothyroxine(for washout period).
• Patients suffering from systemic diseases like Cardiac problem,Diabetes,HTN,Carcinomas etc.
• Patients suffering from Congenital hypothyroidism and Secondary Hypothyroidism.
• Pregnant women,Hyperthyroidism, Neoplasia,Toxic goitre are excluded.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Relief in symptoms	30 days

Secondary Outcome Measures

Name	Time	Method
Decrease TSH level	45 days

Trial Locations

Locations (1)

GOVERNMENT P.G. AYURVEDA COLLEGE AND HOSPITAL; 🇮🇳 Varanasi, UTTAR PRADESH, India

GOVERNMENT P.G. AYURVEDA COLLEGE AND HOSPITAL

🇮🇳Varanasi, UTTAR PRADESH, India

Dr AJAY KUMAR

Principal investigator

9616870871

drajay2000@gmail.com