Graft Patency of the Right Coronary Artery System in OPCAB: Saphenous Vein Graft Versus Right Gastroepiploic Artery
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- All cause mortality
研究概览
简要总结
The ideal grafts for the right coronary artery system in coronary artery bypass surgery remain controversial. The objective of this study is to compare the long-term patency of a right gastroepiploic artery and a saphenous vein graft used for revascularization of the right coronary artery system in off pump coronary artery bypass surgery and to analyze the long-term clinical outcomes.
Total 224 patients will be enrolled according to the randomization protocol.
Check list
-
Laboratories
-
Quantitative coronary analysis (preoperative)
-
Major adverse cardiac and cerebrovascular event
-
coronary CT (coronary angiography if needed) at discharge, 1, 5, 10 years postoperatively
-
Echocardiogram
-
Cardiac enzyme
详细描述
The ideal bypass conduit for the right coronary artery remains a subject of intense controversy. A variety of grafts and configurations are used: the right gastroepiploic artery,the right internal thoracic artery in situ or in a Y-graft configuration,the free radial artery implanted into the aorta or the left internal thoracic artery, and the saphenous vein graft. The influence of the type of graft to the right coronary artery system on clinical results remains poorly documented, and the complementary conduit of choice to this system has yet to be determined. No superior long-term patency rate for any of these grafts to the RCA has been clearly established. We have used a saphenous vein and a right gastroepiploic artery for the right coronary artery system.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Angiographic evidence of severe coronary stenosis on the right coronary territory
- •Elective surgery
- •Isolated off pump CABG
- •Age < 75 years and life expectancy > 5 years
- •Preoperative RGEA diameter > 1.5mm
- •Normal left ventricular function
排除标准
- •History of upper abdomen surgery
- •History of upper GI bleeding
- •Active gastric or duodenal ulcer
- •Body mass index > 35kg/m2
- •Redo surgery
- •Presence of varicose vein
- •Contraindication for CABG such as malignancy or liver cirrhosis
- •Other configuration than RGEA to RCA territory or SVG to RCA territory
结局指标
主要结局
All cause mortality
时间窗: one year
次要结局
- Graft occlusion(one year)