The Spine Kinematics and Center of Pressure Excursion During Functional Task Vertebral Compression Fractures Subjects

Completed

• Conditions: Posture; Vertebral Compression Fracture
• Interventions: Other: no drug intervention

• Registration Number: NCT04135755
• Lead Sponsor: Taichung Veterans General Hospital

Brief Summary

This study aimed to assess the sensory and kinematic components of the limits of stability (LOS) test in patients with vertebral compression fracture (VCF) .

Detailed Description

This study enrolled adults with VCF (VCF group), older adult without spinal deformity (NE group), and young adults (NY group). The Biodex balance system was employed to calculate the balance score and the LOS of participants. An inertia motion system was used to record kinematic data. The center of pressure (COP) signals of postural stability and LOS were used to calculate the frequency power spectrum for interpreting the sensory component.

Study Timeline

• Status Verified: 2015-02
• Study Start: 2015-03-16
• Primary Completion: 2016-08-22
• Study Completion: 2016-08-22
• Study First Submitted: 2019-10-20
• Study First Submitted QC: 2019-10-20
• Study First Posted: 2019-10-23
• Last Update Submitted: 2019-11-02
• Last Update Posted: 2019-11-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 46

Inclusion Criteria

older than 65 years osteoporosis diagnosed by a bone mineral density test of the lumbar spine (T-score < -2.5; T: peak bone mass) thoracic-lumbar VCF on radiography without displacement

Vertebral compression fracture

Exclusion Criteria

other spinal diseases that might also cause back pain (such as scoliosis, lumbar spondylolisthesis, lumbar disk disease, and spinal stenosis) a history of diabetes a history of neurological disease (such as cerebral vascular disease, peripheral neuropathy and vestibular disease).

Control Inclusion Criteria:

None the control participants had evidence of gait, postural, or spine disorders.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
vertebral compression fracture	no drug intervention	No drugs intervention
older adult without spinal deformity	no drug intervention	No drugs intervention
young adults	no drug intervention	No drugs intervention

Primary Outcome Measures

Name	Time	Method
Postural Stability	90 second	A balance system was employed to calculate the standing posture sway score.A high score was indicative of excessive movement during the test and thus, poor stability. The range of value was 0.3- 4.1.
limits of stability	1-2 minutes	patients shift their center of gravity from the center target to a blinking target and back to the center target.This process was repeated for each of the 9 targets. A high score was indicative of fine direction control.The range of value was 21- 66.
Kinematic Data	5 minutes	The movements of the head, upper spine, lower spine, pelvis,hip, thigh, and knee were measured using 6 inertial measurement units.
timed up-and-go test	90 second	sit-stand-walk-180° turning-walk and sitting down task