The impact of collagen peptide versus free amino acid ingestion on myofibrillar and connective tissue protein synthesis rates at rest and during recovery from exercise
- Conditions
- Muscle and connective tissue research (no disorders)Muscle healthSkin health
- Registration Number
- NL-OMON50954
- Lead Sponsor
- niversiteit Maastricht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 57
- Males and females
- Aged between 18-35 years
- Healthy, recreationally active (participating in recreational sports
activities * 3 times per week)
- BMI 18.5 - 30 kg/m2
- No physical limitations (i.e. able to perform all activities associated with
daily living in an independent manner).
- Pregnant
- Third generation oral contraceptives
- Hormone replacement therapy
- Smoking
- Musculoskeletal disorders
- Use of any medications known to affect protein metabolism (i.e.
corticosteroids, non-steroidal anti-inflammatories, or prescribed acne
medications).
- Participation in any structured regular exercise program
- Chronic use of gastric acid suppressing medication or anti-coagulants
- Unstable weight over the last three months
- Pathologies of the gastrointestinal tract
- Blood donation in the past 2 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>To assess the impact of collagen peptides versus free amino acid ingestion<br /><br>after exercise on myofibrillar and connective tissue protein synthesis rates in<br /><br>muscle tissue obtained during recovery from exercise in vivo in humans.</p><br>
- Secondary Outcome Measures
Name Time Method <p>- To assess the impact of collagen peptides versus free amino acid ingestion on<br /><br>connective tissue protein synthesis rates in skin.<br /><br>- To characterize plasma amino acid availability following ingestion of<br /><br>collagen protein versus free amino acids. </p><br>