The effect of N-acetyl cysteine in preventing mucositis in patients undergoing bone marrow transplantatio
Phase 2
- Conditions
- Condition 1: Mucositis (oral). Condition 2: AML. Condition 3: ALL. Condition 4: MDS.Oral mucositis (ulcerative)Acute myeloblastic leukaemiaAcute lymphoblastic leukaemiaMyelodysplastic syndromes
- Registration Number
- IRCT201303301030N13
- Lead Sponsor
- Hematology Oncology and SCT Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 64
Inclusion Criteria
1- Patients receiving chemotherapy regimens (Endoxane- busulfan) in bone marrow transplantation.
2- The patient over the 18 years old of age.
3-Informed consent forms signed by the patients.
Exclusion:
1- Participating in other clinical trial (drug or supplement)
2- Dissatisfaction of patient.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Oral mucositis. Timepoint: Daily at the first day of chemotherapy until the patients discharged. Method of measurement: Clinical observation.
- Secondary Outcome Measures
Name Time Method Glutathione peroxidase serum level. Timepoint: At the first day of admission and 14 days after the transplantation. Method of measurement: Lab Test (ng/dl).;Fever incidence. Timepoint: Daily until discharg. Method of measurement: Measurement of oral temperature.;Duration of neutropenia. Timepoint: Daily until discharg. Method of measurement: Lab Test.;Consumption of TPN. Timepoint: During Hospitalization. Method of measurement: Medical Records.;Antibiotic consumption. Timepoint: During Hospitalization. Method of measurement: Medical Records.