NL-OMON38325已完成不适用
Randomised controlled study of dose reduction and withdrawal strategies of adalimumab and etanercept in rheumatoid arthritis: saving costs at what expense? - DRESS study: Dose REduction Strategies of Subcutaneous TNF inhibitors
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 180
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •- Rheumatoid arthritis (either 2010 ACR RA and/or 1987 RA criteria and/or clinical diagnosis of the treating rheumatologist, fulfilled at any time point between start of the disease and inclusion)
- •- Using either adalimumab or etanercept (all dose/interval regimens, all background medication including DMARDs and corticosteroids up to 5 mg, higher doses of steroids should be reduced first)
- •- 6 months of stable low disease activity while using adalimumab or etanercept (operationalised by either a DAS28 < 3.2 or judgment of low disease activity by rheumatologist at at least two subsequent visits)
- •- 6 months stable treatment with adalimumab or etanercept (previous dose reduction/interval increase is allowed when more than three months ago) and stable DMARDs and corticosteroids for more than 4 weeks
排除标准
- •- Co morbidity that also requires treatment with anti-TNF and thus prevents dose reduction
研究者
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