NCT07590284尚未招募不适用
A Multicenter, Prospective Study of Sonazoid CEUS for Early HCC Surveillance in a High-risk Population
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 556
- 试验地点
- 1
- 主要终点
- Detection rate
研究概览
简要总结
This study is a multicenter, prospective study. In this study, enrolled subjects are cirrhotic patients of any etiology. The US and Sonazoid CEUS monitoring strategy was performed for cirrhotic patients: US and AFP joint with Sonazoid CEUS every 4 to 6 months, and combined CECT/CEMRI every 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Screening
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cirrhotic patients diagnosed clinically or radiologically due to any etiology (patients with cirrhosis due to congenital fibrosis and patients with cirrhosis due to vascular causes were excluded).
- •Age 18-80 years old.
- •Able to receive regular imaging, including US, CEUS, and CECT or CEMRI or EOB-MRI, according to the diagnostic and treatment procedures.
- •Obtained informed consent from the patient.
排除标准
- •Patients with pathologic or enhanced imaging of established HCC who have not undergone curative treatment.
- •Patients with known hypersensitivity to enhanced imaging contrast agents.
- •Patients with severe cardiac, pulmonary or renal insufficiency that precludes CECT or CEMRI or EOB-MRI.
- •Lactating and pregnant women.
- •Those who are not suitable for enrollment as assessed by the investigator.
- •Patients with egg or egg-product allergy, or with severe right-to-left cardiac shunt or intrapulmonary shunt.
研究组 & 干预措施
Sonazoid CEUS and US for screening
Other
Sonazoid CEUS examination
干预措施: Sonazoid CEUS (Diagnostic Test)
结局指标
主要结局
Detection rate
时间窗: 3-year
To compare the detection rate of Sonazoid CEUS and US for early HCC
次要结局
未报告次要终点
研究者
研究点 (1)
Loading locations...
相似试验
招募中
3 期
This Study will be conducted to Evaluate the Safety and Efficacy of Investigational medicine (Efruxifermin) in patients with Compensated Liver Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)/Metabolic Dysfunction-Associated Steatohepatitis (MASH).CTRI/2024/11/076383Akero Therapeutics, Inc.1,150
已完成
不适用
Patient Reported Outcomes In Liver Biopsy (EUS vs. Percutaneous)Chronic Liver Disease (CLD)Liver TransplantationCirrhosisNCT07506642University Hospital Muenster102
已完成
4 期
A Pilot Study of Mirabegron and Montelukast in Cirrhotic PatientsCirrhosisAsthmaNCT07533565Kafrelsheikh University78
尚未招募
Phase 3 4
Comparison of Endoscopic ultrasound and ERCP guided biliary drainageCTRI/2024/02/062850All India Institute of Medical Sciences Rishikesh30
已完成
不适用
easyEndoTM Lite Staplers and Loading Units in Thoracic SurgeryNCT07345013Ezisurg Medical Co. Ltd.900