Embedded Narrative in Interactive Game Design for Improving Medication Adherence of Schizophrenia

Not Applicable

Active, not recruiting

• Conditions: Mental Health Issue; Medication Adherence; Gamification; Schizophrenia and Related Disorders

• Registration Number: NCT06175559
• Lead Sponsor: Zhu Dian

Brief Summary

This study explores the potential of an interactive narrative game to enhance medication adherence among stable schizophrenia patients. Employing participatory design methods, game's development and testing process actively involved patients and individuals closely connected to their daily lives. Artificial Intelligence-Generated Content (AIGC) facilitated swift iterations in game's visual style and content. During game therapy, patients are tasked with making decisions based on presented situations, which influence the course of the narrative.

Detailed Description

Our game design is inspired by Cognitive Behavioral Therapy (CBT), specifically the autonomic engagement and emotion regulation for the treatment of stable schizophrenic patients. This design aims to motivate patients to practice the basic principles of CBT in a virtual environment with the aim of producing positive psychological and behavioral changes in real life.

To ensure that the interactive design in the game can effectively promote cognitive reconstruction and emotional regulation in patients, the investigators used the following game interaction strategies:

1. Situational simulation: By simulating real-life situations, patients face challenges and make decisions in the game that are similar to those in real life, so as to train their cognitive and emotional regulation.

2. Immediate feedback: Provide patients with immediate feedback during the game so that they can understand the impact of their decisions on the outcome of the game, thus encouraging them to make more positive decisions in real life.

3. Role-imitation: Encourage patients to take an in-depth look at their thoughts and behaviors from a third-person perspective by having them take on the role of a therapy practitioner.

Study Timeline

• Study Start: 2023-09-01
• Study First Submitted: 2023-12-08
• Study First Submitted QC: 2023-12-17
• Study First Posted: 2023-12-19
• Status Verified: 2024-04
• Last Update Submitted: 2024-04-17
• Last Update Posted: 2024-04-18
• Primary Completion: 2024-06-01
• Study Completion: 2024-07-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Stable Phase Schizophrenia
• on long-term medication
• medication adherence was problematic

Exclusion Criteria

• Serious Schizophrenia
• Lack of basic cognitive abilities

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
8-item Morisky Medication Adherence Scale , MMAS-8	10 minutes	The MMAS-8 scale is a comprehensive but concise scale that covers multiple dimensions, including participants' understanding of medication, self-management skills, and compliance behavior during treatment. The items have been carefully designed to reveal the difficulties and challenges that patients may face during treatment from different perspectives, and help to fully characterize the dynamics of their adherence behavior.
the In-Game Core Scale (iGEQ)	10 minutes	This questionnaire covers 7 dimensions: immersion, fluency, challenge, positive emotions, negative emotions, uneasiness/irritability, and competence dimensions.

Trial Locations

Locations (1)

Shanghai Jiao Tong University; 🇨🇳 Shanghai, Shanghai, China