Two commonly used anesthesia during cardiac surgery (remifentanil andfentanyl) will be compared; the effect of these anesthesia on thedevelopment of chronic thoracic pain will be measured.
- Conditions
- chronic thoracic pain after cardiac surgery via sternotomyTherapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]
- Registration Number
- EUCTR2013-000201-23-NL
- Lead Sponsor
- St. Antonius Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
All patients living in Utrecht and surroundings undergoing cardiac surgery via sternotomy, including a CABG and/or valve replacement, admitted to the ICU or PACU in the St. Antonius hospital, between 18 and 85 years old, weighing between 45 and 140 kg, written informed consent.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 63
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 63
Exclusion Criteria
- Pregnancy/ breastfeeding
- Language barrier
- History of drug abuse
- Neurologic condition such as peripheral neuropathy
- Known morphine or paracetamol allergy
- BMI > 35 kg/m2
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method