Predicting Responses to Exhausting, Prolonged, And Repeated Exercise Demands (PREPARED) for Heat
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 24
- 试验地点
- 1
- 主要终点
- Core temperature
研究概览
简要总结
The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 39 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy individuals
- •Physically active
排除标准
- •History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
- •Hypertensive (systolic blood pressure > 139 mmHg, diastolic blood pressure > 89 mmHg) or tachycardic (heart rate > 100 bpm) during the screening visit
- •Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
- •Tobacco or nicotine use currently or in the past six months
- •Musculoskeletal injury expected to impact exercise in the protocol
- •A positive pregnancy test at any point in the study
- •Study physician discretion based on any other medical condition or medication
- •Inability to understand or follow instructions or the protocol
- •Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.
研究组 & 干预措施
30/30 work/rest cycle first
Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/30 work/rest cycle (Other)
30/30 work/rest cycle first
Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/20 work/rest cycle (Other)
30/30 work/rest cycle first
Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 40/30 work/rest cycle (Other)
30/30 work/rest cycle first
Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 20/12 work/rest cycle (Other)
30/20 work/rest cycle first
Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/30 work/rest cycle (Other)
30/20 work/rest cycle first
Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/20 work/rest cycle (Other)
30/20 work/rest cycle first
Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 40/30 work/rest cycle (Other)
30/20 work/rest cycle first
Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 20/12 work/rest cycle (Other)
40/30 work/rest cycle first
Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/30 work/rest cycle (Other)
40/30 work/rest cycle first
Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/20 work/rest cycle (Other)
40/30 work/rest cycle first
Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 40/30 work/rest cycle (Other)
40/30 work/rest cycle first
Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 20/12 work/rest cycle (Other)
20/12 work/rest cycle first
Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/30 work/rest cycle (Other)
20/12 work/rest cycle first
Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 30/20 work/rest cycle (Other)
20/12 work/rest cycle first
Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 40/30 work/rest cycle (Other)
20/12 work/rest cycle first
Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion
干预措施: 20/12 work/rest cycle (Other)
结局指标
主要结局
Core temperature
时间窗: 180 minutes of work
Maximum gastrointestinal temperature reached during the work protocol
Isometric mid-thigh pull strength
时间窗: 180 minutes of work
Maximum voluntary contraction strength assessed using a force plate
次要结局
- Vastus lateralis electromyography(180 minutes of work)
- Metabolic cost(180 minutes of work)
- Heart rate(180 minutes of work)
- Mean skin temperature(180 minutes of work)
研究者
Riana Pryor
Assistant Professor
State University of New York at Buffalo