Predicting Responses to Exhausting, Prolonged, and Repeated Exercise Demands (PREPARED) for Heat
- Conditions
- Fatigue; HeatHyperthermia
- Interventions
- Other: 30/30 work/rest cycleOther: 30/20 work/rest cycleOther: 40/30 work/rest cycleOther: 20/12 work/rest cycle
- Registration Number
- NCT06475339
- Lead Sponsor
- State University of New York at Buffalo
- Brief Summary
The overall goal of this project is to identify a work/rest cycle that allows for faster mission completion needed in emergency situations, compared to current Army heat guidance, while mitigating heat strain and neuromuscular fatigue. This project will determine the trade-off between faster mission completion and risk of heat strain and physical performance decrements. Completion of this project will allow military leaders to make informed decisions by understanding the impact of their choices on the magnitude of physical performance decrements and expected heat casualties, setting up hot weather missions for success.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 24
- Healthy individuals
- Physically active
- History of cardiovascular, metabolic (such as clinical thyroid disease), respiratory, neural, or renal disease
- Hypertensive (systolic blood pressure > 139 mmHg, diastolic blood pressure > 89 mmHg) or tachycardic (heart rate > 100 bpm) during the screening visit
- Taking medications or supplements known to effect physiologic responses to exercise or thermoregulation (e.g., beta blockers, omega-3 fatty acids, statins, aspirin)
- Tobacco or nicotine use currently or in the past six months
- Musculoskeletal injury expected to impact exercise in the protocol
- A positive pregnancy test at any point in the study
- Study physician discretion based on any other medical condition or medication
- Inability to understand or follow instructions or the protocol
- Gastrointestinal disease or previous surgery prohibiting core temperature capsule use. Participants with a contraindication can opt to insert the pill rectally as a suppository.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- CROSSOVER
- Arm && Interventions
Group Intervention Description 40/30 work/rest cycle first 30/30 work/rest cycle Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 40/30 work/rest cycle first 40/30 work/rest cycle Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 20/12 work/rest cycle first 30/20 work/rest cycle Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion 20/12 work/rest cycle first 20/12 work/rest cycle Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion 20/12 work/rest cycle first 30/30 work/rest cycle Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/30 work/rest cycle first 30/30 work/rest cycle Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/30 work/rest cycle first 20/12 work/rest cycle Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/20 work/rest cycle first 30/20 work/rest cycle Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/30 work/rest cycle first 30/20 work/rest cycle Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/20 work/rest cycle first 30/30 work/rest cycle Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/20 work/rest cycle first 20/12 work/rest cycle Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion 40/30 work/rest cycle first 20/12 work/rest cycle Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 20/12 work/rest cycle first 40/30 work/rest cycle Participants will first complete the 20/12 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/30 work/rest cycle first 40/30 work/rest cycle Participants will first complete the 30/30 work/rest cycle, and then complete the other three conditions in a randomized fashion 30/20 work/rest cycle first 40/30 work/rest cycle Participants will first complete the 30/20 work/rest cycle, and then complete the other three conditions in a randomized fashion 40/30 work/rest cycle first 30/20 work/rest cycle Participants will first complete the 40/30 work/rest cycle, and then complete the other three conditions in a randomized fashion
- Primary Outcome Measures
Name Time Method Core temperature 180 minutes of work Maximum gastrointestinal temperature reached during the work protocol
Isometric mid-thigh pull strength 180 minutes of work Maximum voluntary contraction strength assessed using a force plate
- Secondary Outcome Measures
Name Time Method Vastus lateralis electromyography 180 minutes of work Wireless electromyography electrodes placed lengthwise over the vastus lateralis muscle belly
Metabolic cost 180 minutes of work Collected expired air using a one-way mask will be analyzed using a metabolic cart to calculate metabolic heat production
Heart rate 180 minutes of work Maximum heart rate measured using a telemetry strap throughout the work protocol
Mean skin temperature 180 minutes of work Maximum skin temperature measured using buttons at four skin sites
Trial Locations
- Locations (1)
Center for Research and Education in Special Environments
🇺🇸Buffalo, New York, United States