Effectiveness and safety of supplement drug (Linfadren®) in the management of patients with post-trauma/surgery persistent ankle edema: a randomized controlled trial

Not Applicable

Completed

• Conditions: persistent ankle edema following trauma or surgery of ankle or distal leg; Musculoskeletal - Other muscular and skeletal disorders; Physical Medicine / Rehabilitation - Physiotherapy; Injuries and Accidents - Fractures; Surgery - Other surgery

• Registration Number: ACTRN12621001040853
• Lead Sponsor: niversity of L'Aquila

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-02-21
• Study Start: 2021-08-09
• Last Update Posted: 17 August 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Inclusion criteria were: 18 years or older, diagnosis of post-trauma/surgery persistent ankle edema with a difference greater than or equal to 20 mm between the affected ankle and the unaffected ankle as measured by figure-of-eight-20 method. Persistent edema was an edema that persisted for more than two weeks.

Exclusion Criteria

Exclusion criteria were: bilateral ankle edema; pulmonary edema; congestive heart failure; coagulation defects; any contraindications limiting clinical evaluation and therapy of the patient.

Study & Design

• Study Type: Interventional
• Study Design: Not specified