Safety and Effectiveness of Fluconazole Versus SCH 56592 to Treat Thrush in HIV-Positive Patients
- Conditions
- Candidiasis, OralHIV Infections
- Registration Number
- NCT00002446
- Lead Sponsor
- Schering-Plough
- Brief Summary
The purpose of this study is to compare the safety and effectiveness of 2 treatments for thrush (a fungal infection of the mouth and throat) in HIV-positive patients. Fluconazole is a drug that is commonly used to treat thrush. SCH 56592 is a new drug that will be compared to fluconazole.
- Detailed Description
Patients receive SCH 56592 oral suspension or fluconazole suspension for 14 days. Patients remain on study for 44 days total and are monitored for safety and efficacy of study treatment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 300
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (18)
ViRx Inc
🇺🇸San Francisco, California, United States
Boulevard Comprehensive Care Ctr
🇺🇸Jacksonville, Florida, United States
Miami Veterans Administration Med Ctr
🇺🇸Miami, Florida, United States
Med Univ of South Carolina
🇺🇸Charleston, South Carolina, United States
Univ of Texas Health Sciences Ctr
🇺🇸San Antonio, Texas, United States
Kaiser Foundation Hospital
🇺🇸San Francisco, California, United States
Dupont Circle Physicians Group
🇺🇸Washington, District of Columbia, United States
TRIAD Health Practice
🇺🇸Chicago, Illinois, United States
Community Hosp Indianapolis
🇺🇸Indianapolis, Indiana, United States
SUNY / Health Science Ctr at Brooklyn
🇺🇸Brooklyn, New York, United States
Infectious Disease and AIDS Clinic
🇺🇸Denver, Colorado, United States
Wayne State Univ / Harper Hosp
🇺🇸Detroit, Michigan, United States
Queen Elizabeth Hosp Respiratory Unit
🇧🇧St Michael, Barbados
Jersey City Med Ctr
🇺🇸Jersey City, New Jersey, United States
Amelia Ct Clinic
🇺🇸Dallas, Texas, United States
East Bay AIDS Ctr
🇺🇸Berkeley, California, United States
Univ of Pennsylvania School of Dental Medicine
🇺🇸Philadelphia, Pennsylvania, United States
UMDNJ - New Jersey Med School / Cooper Hosp
🇺🇸Camden, New Jersey, United States