Study on effects of sage in treatment of hypercholesterolemic type 2 diabetic patients
Phase 2
- Conditions
- Diabetes mellitus.Non-insulin-dependent diabetes mellitus
- Registration Number
- IRCT201506082288N7
- Lead Sponsor
- Iranian Academic Center for Education, Culture and Research Institute of Medicinal Plants
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Iranian male and female type 2 diabetic outpatients; patients aged 40 to 60 years; patients with blood HbA1c levels below 8%; patients with serum LDL levels from 100 mg/dl to 130 mg/dl; patients receiving standard therapy with synthetic anti-hyperglycemic and anti-hyperlipidemic drugs. Exclusion criteria: Patients receiving insulin; patients with cardiac, renal, hepatic, hematological diseases, hypothyroidism, tachycardia, vertigo and seizure; patients with a history of gallstones or gall bladder surgery; patients using estrogen, steroid, beta-blocker and thiazide; pregnant women; women planning pregnancy; breast-feeding women.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fasting serum glucose level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Glycosylated hemoglobin blood level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;LDL serum level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).
- Secondary Outcome Measures
Name Time Method Serum triglyceride level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum total cholesterol level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum creatinine level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum 2 hour postprandial glucose level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum SGOT level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum SGPT level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Serum HDL level. Timepoint: 2 months. Method of measurement: Medical laboratory (kit).;Body mass index. Timepoint: 2 months. Method of measurement: Weighing scales and tape.