French Observatory of Familial Hypercholesterolemia in Cardiology

Terminated

• Conditions: Familial Hypercholesterolemia

• Registration Number: NCT02013713
• Lead Sponsor: French Cardiology Society

Brief Summary

The Family Hypercholesterolemia remains poorly diagnosed disease with an outlet sometimes suboptimal care. However, the Family Hypercholesterolemia exposes patients concerned at increased cardiovascular risk.

The frequency of familial hypercholesterolemia in cardiologic is little studied and remains unknown, and there is little data on the profile of patients, diagnostic methods and management.

Main objectives:

* Establish a monitoring patients with hypercholesterolemia Family cardiology in France

* Characterize the Family hypercholesterolemia in cardiology, including assessing the frequency of the most severe forms, which are at higher cardiovascular risk.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2013-12-06
• Study First Submitted QC: 2013-12-11
• Study First Posted: 2013-12-17
• Study Start: 2014-11
• Primary Completion: 2016-12
• Study Completion: 2016-12
• Status Verified: 2019-08
• Last Update Submitted: 2019-08-06
• Last Update Posted: 2019-08-07

Recruitment & Eligibility

• Status: TERMINATED
• Sex: All
• Target Recruitment: 31

Inclusion Criteria

• coronary patients
• who agreed to participate
• high LDL-c levels: * LDL-c> = 1.9g / l without lipid lowering treatment according to the diagnostic score of Family Hypercholesterolemia these coronary patients with LDL> 1.9g / l may possibly or probably be achieved Hypercholesterolemia Family.

or

* LDL-c> = 1.6g / l in lipid-lowering treatment, the reduction of LDL-c average expected under standard lipid-lowering therapy (statin alone) being 30-40% of these patients had therefore pretreatment levels greater than 2 g / l or greater than 2.5 g / l and may possibly or probably be achieved Family Hypercholesterolemia after the diagnostic score.

Exclusion Criteria

• Expressed refusal to participate in the observatory
• Age ≤ 18

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Frequency of the Family Hypercholesterolemia in cardiology	1 day	Number of Family Hypercholesterolemia among patients with LDL-C\> 1.9g / l without hypoglycemic treatment or\> 1.6g / l in lipid-lowering therapy

Trial Locations

Locations (1)

European Hospital Georges Pompidou; 🇫🇷 Paris, France