Dengue Seroprevalence Study in Blood Donors in the French West Indies
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 817
- 试验地点
- 2
- 主要终点
- Presence or not of dengue virus-specific immunoglobulin G antibodies
研究概览
简要总结
Dengue is an infectious disease most prevalent in the world. This disease is endemic in the Caribbean, with an increase in seasonal rains. Several outbreaks have been observed in recent years, in 2001, 2005 and 2007, during which further particularly virulent serotypes have emerged. The clinical expression of dengue fever is variable, ranging from no symptoms to a classical form with fever, and even of severe or lethal bleeding. With the possible existence of silent forms of the disease, there are no data identifying the current level of protection of the population in Martinique / Guadeloupe.
详细描述
- Principal objective:
To estimate the prevalence of the specific antibodies of the dengue (IgG) in blood donors in the French West Indies. 2. Secondary objective:
To specify the serotypic specificity of the anti-dengue antibodies detected during the study.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Eligible for blood donation following the French legislation,
- •Resident in Martinique /Guadeloupe for at least one year
- •Consent signed
排除标准
- •Not Eligible for blood donation following the French legislation,
- •Not Resident in Martinique / Guadeloupe for at least one year
- •Consent not signed
结局指标
主要结局
Presence or not of dengue virus-specific immunoglobulin G antibodies
时间窗: 1 day
次要结局
- Characterization of dengue virus serotype-specific IgG(1 day)
研究者
RICHARD
Directrice EFS Martinique
Etablissement Français du Sang, Martinique