Prospective observational study on long-term results after glaucoma surgery - substudy: endothelial cell count following Paul Glaucoma Implant surgery

Recruiting

• Conditions: H40; Glaucoma

• Registration Number: DRKS00033596
• Lead Sponsor: Augeklinik und Poliklinik, Universitätsmedizin der Johannes Gutenberg-Universität Mainz

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2024-02-21
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

•Written informed consent to the main study (DRKS00033556)
•Clinic indication for Paul Glaucoma Implant surgery
•Successful peroperative endothelial cell count

Exclusion Criteria

•Previous glaucoma drainage implantation
•Present corneal decompensation
•Language barrier
•Withdrawal of planned surgery
•Patients without ability to consent or minors
•Patients with known addictions

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Change of endothelial cell count (loss) in patients with Paul Glaucoma Implant surgery peroperatively to 24 months postoperatively at the central cornea

Secondary Outcome Measures

Name	Time	Method
- endothelial cell count (ECC) follow-up curve over 24 months (at 3, 6, 12, and 24 months; central cornea and in all quadrants)<br>- relationship between ECC loss and tube position between iris and corneal endothelium<br>- course of corneal tomography using Scheimpflug imaging<br>- frequency of impaired ocular motility following Paul Glaucoma Implant surgery<br>- other endpoints investigated in the main study (DRKS00033556)