Effect of giving iron injection in acute heart failure patient.

Not Applicable

• Conditions: Health Condition 1: - Health Condition 2: I509- Heart failure, unspecified

• Registration Number: CTRI/2023/10/058522
• Lead Sponsor: ot applicable

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

I) Age >18 years.

ii) NYHA class III and IV.

iii)Bilateral B-lines on lungs ultrasonography.

iv) Left ventricular ejection fraction less than 50%.

v) Serum ferritin level less than 100 ng/ml or serum ferritin more than 200ng/ml with transferrin saturation less than 20%.

vi)Patients / Legally authorised representative willing to give valid consent.

Exclusion Criteria

I) Individuals/ legally authorized representative unwilling to give written consent for participation in the study.

ii)Acute coronary syndrome OR Acute myocardial infarction within one month.

iii) Rheumatic valvular heart disease.

iv) History of blood transfusion in last one month.

v) known history of hypersensitivity to any component of intravenous iron.

vi) patient on mechanical ventilation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
I) To study clinical improvement using NYHA grading in an iron deficient patient with Acute Decompensated Heart Failure after intravenous iron therapy. <br/ ><br> <br/ ><br>II) To evaluate the rate of rehospitalization within one month after intravenous iron therapy in iron group versus placebo group in an iron deficient patient with Acute Decompensated Heart Failure. <br/ ><br>Timepoint: one and half year <br/ ><br>

Secondary Outcome Measures

Name	Time	Method
I) To study effect of intravenous iron therapy on ejection fraction improvement in an iron deficient patient with Acute Decompensated Heart Failure at one month. <br/ ><br>ii) To study effect of intravenous iron on mortality at one month in an iron deficient patient with Acute Decompensated Heart Failure. <br/ ><br>Timepoint: one and half year