The roles of impulse oscillometry in detection of asthma control level.

Not Applicable

Active, not recruiting

• Conditions: Clinical diagnosed- asthma patients with age ≥ 20 years.; asthma, airway resistance, pulmonary function

• Registration Number: TCTR20190709004
• Lead Sponsor: Faculty of Medicine, Chiang Mai University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2019-07-09
• Study Completion: 2020-06-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 187

Inclusion Criteria

The study population will be recruited according to the following criteria:

1. Asthma group
-Clinical diagnosed-asthma aged ≥ 20 years old
-Clinical diagnosed-asthma based on episode breathlessness, wheezing, cough, and tightness after incidental allergen exposure and/or bronchodilator responsiveness (≥ 12% and 200 milliliter increase in FEV1 after 2-4 puffs of salbutamol.
-No history of chronic respiratory diseases other than asthma
-Non-smokers or ex-smoker < 5 packs-year
-Stable disease with controller medication for at least 6 weeks
-Controller medication used for at least 3 month

Healthy group
-Healthy subjects aged ≥ 20 years old
-No history of chronic respiratory diseases
-Non-smokers or ex-smoker < 5 packs-year
-Normal spirometry

Exclusion Criteria

The study population will be excluded from the study according to the following criteria:
- Unable to perform spirometry
- Unable to perform IOS
- Spirometry not met American Thoracic Society (ATS)/ European Respiratory Society (ERS) 2005 standard
- IOS not met standard recommended by Bickel et al and ERS standard

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Cut off point of IOS parameter for diagnosis COPD 0 min (baseline) cmH2O

Secondary Outcome Measures

Name	Time	Method
ROC curve of IOS parameter for diagnosis COPD 0 min (baseline) percent