Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 82
- 试验地点
- 1
- 主要终点
- stone clearance
研究概览
简要总结
Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •single upper ureteric stone
- •size ranging from 6-15 mm
- •stones history less than 6 months
排除标准
- •Patients with urinary tract infection
- •multiple ureteric stones,
- •presence of a ureteric stricture distal to the stone,
- •previous unsuccessful ESWL,
- •concomitant use of calcium channel blockers or alpha-adrenergic antagonists
- •patients with abnormal coagulation profile
结局指标
主要结局
stone clearance
时间窗: 4 weeks
Number of patients cleared from ureteric stones
次要结局
未报告次要终点
研究者
Dr. SamiUllah
Principal Investigator
Services Hospital, Lahore