Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy
- Conditions
- Renal Stone
- Registration Number
- NCT05725122
- Lead Sponsor
- Services Hospital, Lahore
- Brief Summary
Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 82
- single upper ureteric stone
- size ranging from 6-15 mm
- stones history less than 6 months
- Patients with urinary tract infection
- multiple ureteric stones,
- presence of a ureteric stricture distal to the stone,
- previous unsuccessful ESWL,
- concomitant use of calcium channel blockers or alpha-adrenergic antagonists
- patients with abnormal coagulation profile
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method stone clearance 4 weeks Number of patients cleared from ureteric stones
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
services Institute of Medical Sciences
🇵🇰Lahore, Punjab, Pakistan
services Institute of Medical Sciences🇵🇰Lahore, Punjab, Pakistan