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Based-virtual Reality Diagnosis for Neuropsychiatric Diseases and Sleep/Wake Disorders

Not Applicable
Conditions
Addiction
Aging
Attention Deficit
Attention Deficit Disorder With Hyperactivity
Sleep Disorders
Anxiety
Depression
Interventions
Behavioral: Clinical interview
Behavioral: Virtual reality task
Registration Number
NCT02544295
Lead Sponsor
University of Bordeaux
Brief Summary

The objective of this research is to develop original virtual reality scenarios and/or new virtual reality equipments to evaluate or diagnose pathologies, such as attention deficit disorders or neuropsychiatric pathologies, addiction, anxiety or depression or pathologies interfering with sleep/wake disorders.

Detailed Description

Nature of the trial: without direct individual benefit study conducted in healthy volunteers, patients with attention disorders : ADHD (Attention Deficit Disorder / Hyperactivity) and cognitive aging, addictive disorders, anxiety disorders, depressive disorders or pathologies that interfere with sleep/wake cycle. The duration of the study is 8 years.

Type of trial: Comparison of two parallel groups of healthy volunteers and patients with attention disorders, addictive, anxious, depressive or interfering with sleep/wake cycle.

Study design:

* standardized clinical interview with a sleep specialist, psychiatrist, or psychologist and rating scales,

* a virtual reality task. The primary outcome is to evaluate the diagnosis accuracy and the acceptability of the virtual tool to the referent standard (clinical interview and scales).

The secondary outcomes are:

* The comparison of healthy subjects and patients performances

* Tolerance, acceptability to exposure to virtual scenarios.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
590
Inclusion Criteria
  • Being aged between 7 and 75 years
  • Having signed written informed consent
Exclusion Criteria
  • Having participated to a clinical trial in the previous 3 months

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Clinical interview-Virtual reality task:1Virtual reality taskHealthy controls will be assessed by a clinical interview by a psychiatrist, once, 1 day-duration and Virtual reality task, once, 1 day-duration
Clinical interview-Virtual reality task:2Virtual reality taskPatients will be assessed by a clinical interview by a psychiatrist, once, 1 day-duration and Virtual reality task, once, 1 day-duration
Clinical interview-Virtual reality task:1Clinical interviewHealthy controls will be assessed by a clinical interview by a psychiatrist, once, 1 day-duration and Virtual reality task, once, 1 day-duration
Clinical interview-Virtual reality task:2Clinical interviewPatients will be assessed by a clinical interview by a psychiatrist, once, 1 day-duration and Virtual reality task, once, 1 day-duration
Primary Outcome Measures
NameTimeMethod
Presence or absence of the disease1 day

Categorial diagnosis generated by the psychiatrist and by the Virtual reality task (0=absence of disease and 1 = presence of the disease)

Secondary Outcome Measures
NameTimeMethod
Sleepiness scale1 day

Scores range from 0 (no sleepiness) to 24 (severe sleepiness)

BDI-II questionnaire1 day

Beck Depression Inventory Scores range from 0 (no depression) to 63 (severe depression)

Physiological parameters: Polysomnography (sleep structure (stage %))1 night
Physiological parameters: Polysomnography (Apnea/Hypopnea index and Periodic movements index (events/hr))1 night
Physiological parameters: Polysomnography (total sleep time (min))1 night
IDS-R questionnaire1 day

Inventory of Depressive Symptomatology scores range from 0 (no depression) to 84 (severe depression)

Acceptability scale1 day

Scores range from 0 to 36

ASRS1 day

Adult ADHD Self-Report Scale Scores : Four or more positive answers in Part A (6 questions) are indicative of ADHD symptoms.

Trial Locations

Locations (1)

University Hospital of Bordeaux

🇫🇷

Bordeaux, France

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