Evaluating the prevalence of Coeliac disease in children with Developmental Defects of Enamel

Not Applicable

• Conditions: Coeliac Disease; Dental Caries; Inflammatory and Immune System - Autoimmune diseases; Diet and Nutrition - Other diet and nutrition disorders; Oral and Gastrointestinal - Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon

• Registration Number: ACTRN12622000403730
• Lead Sponsor: Coeliac Australia

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-03-09
• Last Update Posted: 8 May 2023

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

1) Subjects greater than or equal to two (2) years of age, though less than or equal to 18 with/without developmental defects of enamel identified at the time of a dental review.
2) The subject or their guardian (if under 16 years of age) understands and agrees to the informed consent form (ICF).
3) Consuming gluten in their diet on a daily basis, at no less than four pieces of bread per day, or at least one gluten containing meal per day.

Exclusion Criteria

1)Subject has been on a strict gluten free diet or limiting gluten for more than month prior to recruitment.
2)Subject is or has been using an immune-modulatory or immune suppressive therapy during the six months prior to recruitment.
3)Subject has received oral or parenteral corticosteroids within the previous 8 weeks prior to recruitment. Topical or inhaled corticosteroids are acceptable.
4)Unable to provide written informed consent.
5)Unwilling to undergo a pin-prick test.

Study & Design

• Study Type: Observational
• Study Design: Not specified