NCT01750333Unknown不适用
Observational Retrospective Study on Correlation Between ET-1 and Ad in Obese Children
Monica Montagnani1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2012年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Correlation between serum levels of ET-1 and Ad in lean, overweight and obese children
研究概览
简要总结
The aim of this study is to explore whether and how high circulating levels of endothelin-1 (ET-1) in obese and overweight children may contribute to impair adiponectin (Ad) production, release and vascular activity
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 5 Years 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children will be enrolled into lean, overweight or obese groups based on Body mass index (BMI) calculated according to standard methods. International standards for sex-and age-specific BMI centiles for subjects aged 2-18 years will be used. The 95th centile of BMI reference is the cut off point for childhood obesity. Overweight and obese children are defined as those with a BMI higher than the centile curves.
排除标准
- •presence of renal, liver and/or cardiovascular diseases;
- •hypertension;
- •metabolic and/or endocrine disorders;
- •genetic syndromes;
- •histories of chronic allergies, acute infectious or inflammatory diseases during the last 3 months preceding the study
结局指标
主要结局
Correlation between serum levels of ET-1 and Ad in lean, overweight and obese children
时间窗: 12 months
次要结局
未报告次要终点
研究者
Monica Montagnani
Medical School Faculty Member - Professor of Pharmacology
Montagnani, Monica, M.D., Ph.D.
研究点 (1)
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