Timing of Prophylactic Antibiotics for Cesarean Sections

Not Applicable

Completed

• Conditions: Wound Infection; Endometritis

• Registration Number: NCT00330278
• Lead Sponsor: Medical University of South Carolina

Brief Summary

This is a randomized, double-blinded placebo controlled trial of cefazolin timing before cesarean section fo infection prophylaxis. Subjects are randomized to cefazolin either 30 minutes prior to skin incision or at time of cord-clamping. Primary outcome is infectious morbidity including wound infections and endometritis.

Detailed Description

Not available

Study Timeline

• Study Start: 2003-01
• Status Verified: 2006-01
• Study Completion: 2006-01
• Study First Submitted: 2006-05-25
• Study First Submitted QC: 2006-05-25
• Study First Posted: 2006-05-26
• Last Update Submitted: 2007-09-26
• Last Update Posted: 2007-09-27

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 350

Inclusion Criteria

Pregnant 24-43 weeks gestation > 18 years old Requiring cesarean section -

Exclusion Criteria

Receiving antibiotics < 18 years old Allergy to cefazolin

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Combined infectious morbidity - endometritis + wound infection

Secondary Outcome Measures

Name	Time	Method
Neonatal sepsis
Allergic reactions

Trial Locations

Locations (1)

Medical University of South Carolina; 🇺🇸 Charleston, South Carolina, United States