The Prevalence and Characteristics of Adrenal Incidentaloma: A Prospective Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25,356
- 试验地点
- 1
- 主要终点
- Prevalence and Characteristics of Adrenal Incidentaloma
研究概览
简要总结
To investige the prevalence, characteristics and prognosis of adrenal incidentalomas in Chinese adults.
详细描述
With the development of imaging detection technology and its wide application in clinic, the detection rate of adrenal incidentaloma (AI) has been greatly improved. Most AI are benign and do not have the function of autonomic hormone secretion, but about 20% of them have function and can secrete adrenal hormone autonomously. Studies based on biopsy reports show that the prevalence of AI is about 2%, and the prevalence of AI detected by CT scan is 1% - 4.5%. However, most of these studies are retrospective, and there may be selection bias and other confounding factors. There is no large sample prospective study on the prevalence of AI in the general population. The purpose of this study is to prospectively include patients with adrenal incidentaloma in community physical examination population, and evaluate their function and prognosis. The research results will provide new evidence for standardized diagnosis and treatment of adrenal incidentaloma in the future.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 78 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •·On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study.
排除标准
- •with known adrenal diseases;
- •with continuous steroids or drug treatment that might influence cortisol secretion ordexamethasone metabolism and could not be stopped
- •refuse to participate in the study.
结局指标
主要结局
Prevalence and Characteristics of Adrenal Incidentaloma
时间窗: 1 years
To investigate the prevalence and characteristics of Adrenal Incidentaloma in general population in China
次要结局
- Steroid hormones in the function of Adrenal Incidentaloma(1 years)
研究者
Qifu Li
Prof.
Chongqing Medical University
