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Febrile Urinary Tract Infection Randomized Short Treatment Trial.

Recruiting
Conditions
urinary tarct infection, acute pyelonephritis, urosepsis
Registration Number
NL-OMON20802
Lead Sponsor
eiden University Medical Center
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
400
Inclusion Criteria

1. Competent patient aged 18 years or above;

2. One or more symptom(s) suggestive of urinary tract infection (dysuria, frequency or urgency*; perineal or suprapubic pain; costo-vertebral tenderness or flank pain);

Exclusion Criteria

1. Known allergy to fluoroquinolones;

2. Female patients who are pregnant or lactating;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The clinical cure rate through the 10- to 18-day posttherapy visit. Clinical cure is defined as the resolution of fever and signs and symptoms of UTI.
Secondary Outcome Measures
NameTimeMethod
This includes microbiological cure rate 10- to 18-day posttherapy, 30- and 90- day overall mortality rate, clinical cure rate 70- to 84- day posttherapy, time to resolution of symptoms, relapse rate of UTI, adverse events or complications, rate of pelvic floor dysfunction as assessed by a standardize questionaire and the occurrence of Clostridium difficile disease.
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