Demineralized Dentin Graft With Hydrochloric Acid Versus Nitric Acid in Alveolar Ridge Preservation. Randomised Controlled Clinical Trial
试验速览
- 阶段
- 不适用
- 入组人数
- 8
- 主要终点
- Radiographic bone changes
研究概览
简要总结
The reduction in alveolar bone dimensions is an inevitable outcome after tooth extraction due to the healing events that results in bone modeling/remodeling. Alveolar ridge preservation is a successful approach that aids in reducing these changes greatly. Various techniques have been employed to achieve that outcome utilizing bone grafts and/or membrane. Dentin graft is a promising type that can overcome many of the limitations facing mainstream grafts. Autogenous source serve the advantage of providing graft with no cross-infection risk or immunogenicity. Moreover, the unique structure of dentin makes it suitable for osteoinduction and osteoconduction that yields favorite bone regeneration outcomes. Demineralization of dentin is essential to release trapped growth factors, expose collagen fibrils and enhance the grafts degradability and replacement by native tissues. Many acids have been investigated for the use in chairside preparation of the dentin graft and hence, clinicians are faced with different choices but little evidence regarding the acid which yield s better outcomes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 60 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Non-restorable teeth
- •medically healthy
- •able to provide informed consent and attend follow-up period
排除标准
- •smokers or alcoholic
- •severe bone loss
结局指标
主要结局
Radiographic bone changes
时间窗: 6 months
width and height losses (quantitative in mm)
次要结局
- soft tissue healing(Biweekly for 6 weeks)
- histological analysis(6 months)
研究者
Ahmed Mohamed AbdelRaouf Hussein
Principal investigator
Cairo University
