NCT05700032撤回不适用
The Impact of High Mechanical Index Ultrasound Impulses on Left Ventricular Stroke Volume in Patients Receiving Intravenous Microbubbles
适应症
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 主要终点
- Left Ventricle Outflow Tract (LVOT) First Ventilatory Threshold VTI
研究概览
简要总结
This study will investigate whether applying high mechanical index (MI) impulses from a diagnostic ultrasound transducer when using ultrasound enhancing agent (UEA) microbubble infusion will result in subclinical improvement in left ventricle systolic function.
详细描述
The purpose of this study is to investigate whether applying high MI impulses from a diagnostic ultrasound transducer when using ultrasound enhancing agent(UEA) microbubble infusion will result in subclinical improvement in LV systolic function detected by left ventricular outflow tract velocity time integral (LVOT VTI).
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 19 years or older
排除标准
- •severe aortic valve stenosis
- •pregnant or lactating women
- •atrial fibrillation
- •very poor image quality despite contrast use.
- •unstable cardiac condition such as cardiogenic shock.
- •allergy to UEA
- •presence of right to left or bidirectional shunts.
- •Patients on mechanical circulatory support.
结局指标
主要结局
Left Ventricle Outflow Tract (LVOT) First Ventilatory Threshold VTI
时间窗: 10 minutes
Left Ventricle Outflow Tract (LVOT) First Ventilatory Threshold VTI
次要结局
- stroke volume(10 minutes)
研究者
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