The Immediate Effect of Combined Terminal Knee Extension Exercise With Audible Cues

Not Applicable

Recruiting

• Conditions: Muscle Weakness
• Interventions: Behavioral: Exercise + Audible Cues; Behavioral: Exercise

• Registration Number: NCT06565325
• Lead Sponsor: Mahidol University

Brief Summary

Typically, patients perform TKE by themselves after exercise prescription. The investigators thought that a lack of attention and preferred speed of patients might not provide the best outcome. Therefore, an increased effectiveness of TKE is interesting for physical therapy implication. Besides, adding sensory input which is audible cues or rhythm during exercise may enhance the efficacy of the exercise by increasing neuromuscular control and function.

Therefore, the study aimed to investigate the immediate effects of combined TKE with audible cues on motor unit behavior. The researchers expect that adding rhythm from the metronome will enhance neuromuscular control which may change motor unit behavior of VM muscle. The findings of the study may have helped explain the mechanism behind the acute effects of combined TKE with audible cues on VM function and their potential application in the field of physical therapy.

This study aims to investigate the immediate effect of combined TKE with audible cues on motor unit behavior in healthy participants and to investigate reliability of decomposition electromyography procedure during single leg squat.

Detailed Description

A metronome will be used to provide rhythmic exercise. Participants will stand with their feet in line with their shoulders as starting position and straping at the knee. Exercise intensity is 60% of the 1RM weight. At the beginning of the exercise, participants will be asked to bend their knees following the pull of the resistance and exert force to straighten the knee (10 times/set and 3 sets). 180 seconds of resting will be allowed between sets.

Study Timeline

• Study Start: 2024-02-10
• Status Verified: 2024-08
• Study First Submitted: 2024-08-11
• Study First Submitted QC: 2024-08-20
• Last Update Submitted: 2024-08-20
• Study First Posted: 2024-08-21
• Last Update Posted: 2024-08-21
• Primary Completion: 2025-02-07
• Study Completion: 2025-02-07

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 30

Inclusion Criteria

• Aged range between 18 and 30 years
• BMI of 18.5-25 kg/m2
• Male or female
• Lightly active or sedentary {Physical activity level (PAL= 1.4-1.69)}

Exclusion Criteria

• History of serious injury or operation of lower back and lower extremities such as fracture
• Musculoskeletal problems of lower back and lower extremities in 6 months before the study
• Single-leg stance test < 43 seconds (26). and range of weight-bearing lunge test < 9.1 cm

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Experimental group	Exercise + Audible Cues	Terminal Knee Extension Exercise with Audible Cues
Control group	Exercise	Terminal Knee Extension Exercise without Audible Cues

Primary Outcome Measures

Name	Time	Method
Motor unit firing rate	At the end of Cycle 1 (each cycle is 1 day)	one parameter to explain the motor unit behavior of vastus medialis muscle
Peak motor action potential	At the end of Cycle 1 (each cycle is 1 day)	one parameter to explain the motor unit behavior of vastus medialis muscle

Trial Locations

Locations (1)

Faculty of Physical Therapy, Mahidol University; 🇹🇭 Nakhon Pathom, Salaya, Thailand