Effect of supplementation in treatment of women with polycystic ovary syndrome

Phase 3

Conditions: Polycystic ovary syndrome.
Polycystic ovarian syndrome
E28.2

Registration Number: IRCT201605215623N79

Lead Sponsor: Vice chancellor for research, Arak University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: Female

Target Recruitment: 40

Inclusion Criteria

Patients with PCOS according to Rotterdam criteria aged 18 to 40 years

Exclusion Criteria

Smoking
Intake of omega-3 fatty acids and/or vitamin E supplements within the last 3 months
Intake of anti-inflammatory or antidiabetic drugs
Pregnancy
Other causes of hyperandrogenism and/or anovulation

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Beck scor. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Questionnaire.;GHQ score. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Questionnaire.;DASS-28 score. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: Questionnaire.

Secondary Outcome Measures

Name	Time	Method
evel of IL-1 gene expression. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: PCR.;Level of IL-8 gene expression. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: PCR.;Level of TNFa gene expression. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: PCR.;Level of TGFB gene expression. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: PCR.;Gene expression of PPAR-gamma. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: PCR.;Gene expression of GLUT-1. Timepoint: At the beginning of the study and after 12 weeks of intervention. Method of measurement: PCR.