Cold Snare Polypectomy Vs. Cold Forceps Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps

Not Applicable

Completed

• Conditions: Polyp of Large Intestine
• Interventions: Device: Cold snare polypectomy; Device: Cold biopsy polypectomy

• Registration Number: NCT02201147
• Lead Sponsor: Soonchunhyang University Hospital

Brief Summary

The purpose of this study is to compare cold snare polypectomy and cold forceps polypectomy using narrow-band imaging endoscopy for removal of diminutive colorectal polyps.

Detailed Description

Previous study found Cold snare polypectomy a preferable technique in comparison to cold biopsy for diminutive polyps when assessed for completeness of resection. However, it is expected that cold biopsy polypectomy with advanced endoscopy, such as chromoendoscopy or narrow-band imaging endoscopy, increase completeness of resection. One study showed 90% of the diminutive polyps were completely resected using cold biopsy polypectomy with chromoendoscopy. However, no study compared cold snare polypectomy and cold biopsy polypectomy using Narrow-band Imaging endoscopy for Removal of Diminutive Colorectal Polyps.

The aim of this study is to compare cold snare polypectomy and Cold biopsy Polypectomy Using Narrow-band Imaging Endoscopy for Removal of Diminutive Colorectal Polyps

Study Timeline

• Study Start: 2014-07
• Study First Submitted: 2014-07-22
• Study First Submitted QC: 2014-07-24
• Study First Posted: 2014-07-25
• Primary Completion: 2014-11
• Study Completion: 2014-11
• Status Verified: 2015-05
• Last Update Submitted: 2015-05-02
• Last Update Posted: 2015-05-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 146

Inclusion Criteria

• patients over the age of 20 years undergoing routine colonoscopy (screening, surveillance, or diagnostic)

Exclusion Criteria

• patients taking antiplatelet or anticoagulant therapy during the past 1 week of the procedure
• known coagulopathy
• history of inflammatory bowel diseases
• American Society of Anesthesiology class III or more
• pregnancy.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Cold snare polypectomy	Cold snare polypectomy	-
cold biopsy polypectomy	Cold biopsy polypectomy	-

Primary Outcome Measures

Name	Time	Method
complete histologic polyp eradication rate	2 weeks

Secondary Outcome Measures

Name	Time	Method
rates of tissue retrieval per polyp	2 weeks

Trial Locations

Locations (1)

Soonchunhyang University Hospital, Bucheon; 🇰🇷 Bucheon, Korea, Republic of